ArticleJournal of thoracic disease2024
Association between health-related quality of life and perioperative exercise capacity in older postoperative patients with non-small cell lung cancer.
Article in Journal of thoracic disease, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed.
- Association between Inpatient Moderate-to-vigorous Physical Activity and Functional Recovery following Lung Resection for Neoplastic Lung Diseases.Progress in rehabilitation medicine · 2026Article
- Are there different phenotypes of thoracic surgery patients? A latent class analysis of pretreatment patient-reported outcomes.JTCVS open · 2025Article
- Risk analysis of cardiac disease mortality within 3 months in patients with lung cancer after surgery: A real-world cohort study.The Journal of international medical research · 2025Article
- Generalization of the findings from the article on the association between health-related quality of life and perioperative exercise capacity in older postoperative patients with non-small cell lung cancer.Journal of thoracic disease · 2025Article
- Critical considerations for assessing quality of life and physical recovery in elderly patients after lung resection.Journal of thoracic disease · 2025Article
Corrections and comments
- Commented on by
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Lung cancer represents a significant global health concern and constitutes the primary cause of cancer-related mortality. Complete surgical resection with curative intent remains the most efficacious treatment modality for improving the survival rate of patients with localized lung cancer. Average life expectancy has increased in many countries, and the number of older patients undergoing surgery has increased. We aimed to evaluate the change in health-related quality of life (HRQOL) during perioperative lung resection and the association between HRQOL and perioperative physical function (PF) in older patients with lung cancer. Methods: This prospective observational study was conducted in a single tertiary university hospital. Patients aged ≥70 years who underwent lung resection between 1 April 2013 and 31 December 2020 were included. HRQOL was assessed utilizing the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core 30 (EORTC QLQ-C30) preoperatively and at 1, 3, and 6 months postoperatively. PF was evaluated using the handgrip, quadriceps force, and 6-minute walking distance (6MWD) tests preoperatively and 1 week after surgery. We analyzed a model for total HRQOL and each domain of HRQOL scores at different time points using a mixed-effects model for repeated measures. A multiple regression analysis was performed to estimate the associations between changes in total HRQOL scores following surgery and clinically relevant factors. Results: In total, 260 patients (172 with stage IA disease, 162 men; median age, 75 years) were included in the analysis. The median preoperative total HRQOL score was 90.1 points, while the scores at postoperative 1, 3, and 6 months were 81.5, 87.5, and 87.4 points, respectively. The total HRQOL score at baseline and the decline in postoperative 6MWD were significant predictors of the total HRQOL score at each time point. Conclusions: HRQOL recovered to preoperative levels 3 months after surgery; the 6MWD decrease before and after surgery was associated with HRQOL recovery than other clinically relevant factors. These results suggest the importance of active early mobilization in preventing functional decline during hospitalization and continuing exercise training after discharge.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.