Evidence map›Paper›PMID 39831220›Full record

ArticleJournal of thoracic disease2024

Case series on the use of the indocyanine green fluorescence real-time imaging technique for lymph node sorting in patients undergoing radical esophagectomy.

Xiao Wang, Weixin Liu, Xiaodan Hu, Yangle Zhao, Yun Zhao, Xingxing Xue, Xiaogang Liu, Lining Wang, Thomas Bauer, Jian Cui and 1 more

Abstract read
In one paragraph

Article in Journal of thoracic disease, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Xiao Wang *Department of Thoracic Surgery, Beijing Chuiyangliu Hospital, Beijing, China.ORCID https://orcid.org/0009-0005-5506-9827
Weixin Liu *Department of Thoracic Surgery, Cancer Hospital, Chinese Academy of Medical Sciences, Beijing, China.
Xiaodan HuDepartment of Thoracic Surgery, Beijing Chuiyangliu Hospital, Beijing, China.
Yangle ZhaoDepartment of Thoracic Surgery, Beijing Chuiyangliu Hospital, Beijing, China.
Yun ZhaoDepartment of Thoracic Surgery, Beijing Chuiyangliu Hospital, Beijing, China.
Xingxing XueDepartment of Thoracic Surgery, Beijing Chuiyangliu Hospital, Beijing, China.
Xiaogang LiuDepartment of Thoracic Surgery, Beijing Chuiyangliu Hospital, Beijing, China.
Lining WangDepartment of Thoracic Surgery, Beijing Chuiyangliu Hospital, Beijing, China.
Thomas BauerDepartment of Surgery, Jersey Shore University Hospital, Neptune, NJ, USA.
Jian CuiDepartment of Thoracic Surgery, Beijing Chuiyangliu Hospital, Beijing, China.
Yong LiDepartment of Thoracic Surgery, Cancer Hospital, Chinese Academy of Medical Sciences, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: There is a clear correlation between accurate postoperative lymph node staging and the survival prognosis of patients. This study aimed to explore the application and value of indocyanine green (ICG) fluorescence real-time imaging technology in lymph node sorting during radical esophagectomy for esophageal cancer. Methods: From August 2022 to June 2023, the specimens of 66 patients who underwent esophageal cancer resection with lymph node dissection were examined. Among them, 12 cases of Results: A total of 329 lymph nodes were detected in the 12 patients with an average of 29.75±9.19 nodes per patient. Lymph node metastasis was detected in five patients, of whom, three were diagnosed as N1 (N refers to regional lymph nodes, N1: involves 1 to 2 regional lymph node metastases), and two were diagnosed as N2 (N refers to regional lymph nodes, N2: involves 3-6 regional lymph node metastases). Following the ICG injection of 12 patient specimens, lymph nodes were re-detected in 6 patients of them (above we stated 12 patients), yielding a detection rate of 50%. In total, 17 lymph nodes were detected. There was a statistically significant difference in the total number of lymph nodes detected before and after the injection of ICG (P=0.02). Among the other 54 patients, an average of 34.06±15.66 lymph nodes were detected. There was no statistically significant difference in the total number of lymph nodes detected between the two groups (P=0.21). Conclusions: The use of ICG fluorescence real-time imaging technology facilitate lymph node identification in resected specimens and will become a powerful technique for precise staging in esophageal cancer treatment.

Indexed as

case seriesfluorescence real-time imaging technologyIndocyanine green (ICG)lymph node sortingradical esophagectomy

Identifiers

PMID39831220
PMCPMC11740062

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.