Evidence map›Paper›PMID 39830886›Full record

ArticleToxicology research2025

Evaluation of acute substance abuse patients admitted to the ICU by different scoring system.

Wafaa Mohamed Mahmoud El Sehly, Fatma Mohamed Magdy Badr El Dine, Nahla Ahmed Gamal El Dine, Sara Gamal Kamal Elnwam, Rasha Ismail Khedr

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Article in Toxicology research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Wafaa Mohamed Mahmoud El SehlyDepartment of Forensic Medicine and Clinical Toxicology, Champollion street, Faculty of Medicine, University of Alexandria, Alexandria, 21517, Egypt.
Fatma Mohamed Magdy Badr El DineDepartment of Forensic Medicine and Clinical Toxicology, Champollion street, Faculty of Medicine, University of Alexandria, Alexandria, 21517, Egypt.
Nahla Ahmed Gamal El DineDepartment of Public Health and Community Medicine Faculty of Medicine, University of Alexandria, Alexandria, smouha, 21604, Egypt.
Sara Gamal Kamal ElnwamDepartment of Forensic Medicine and Clinical Toxicology, Champollion street, Faculty of Medicine, University of Alexandria, Alexandria, 21517, Egypt.
Rasha Ismail KhedrDepartment of Forensic Medicine and Clinical Toxicology, Champollion street, Faculty of Medicine, University of Alexandria, Alexandria, 21517, Egypt.ORCID https://orcid.org/0000-0002-7070-173X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Drug abuse poisoning is a significant public health problem in many countries all over the world. The recent study aimed to assess the applicability of NEWS II and APACHE II scores as predictors of the ICU admission of acute intoxication by substance abuse. The study enrolled 98 patients admitted to the Alexandria Poison Center of the Main University Hospital (APC-AMUH) with a history of acute intoxication with substance abuse. Collected data included socio-demographic data, circumstances of exposure, and clinical and laboratory data. These data were employed to calculate NEWS II and APACHE II scores. A total of 98 substance abuse patients were admitted. Morphine constituted the highest percentage of substance intoxication (33.7%), followed by methanol (23.5%) and tramadol (17.3%). About one-third of the patients needed the ICU admission (32.7%). The median of NEWS and APACHE II was 7. The mean values of NEWS II and APACHE II in patients who entered the ICU were significantly higher than in patients who did not enter the ICU. The cut-off value of the ROC curve of NEWS II and APACHE II scores for admission to the ICU was 8 for both. These findings suggest that NEWS II and APACHE II scores are good predictors for the evaluation of patients intoxicated by substance abuse who need ICU admission.

Indexed as

APACHE IINEWS IIopioidsscoring systemsubstance abusetramadol

Identifiers

PMID39830886
PMCPMC11739804

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