Evidence map›Paper›PMID 39830836›Full record

ArticleCritical care explorations2025

Investigation of a Novel Noninvasive Risk Analytics Algorithm With Laboratory Central Venous Oxygen Saturation Measurements in Critically Ill Pediatric Patients.

Sarah A Teele, Avihu Z Gazit, Craig Futterman, William G La Cava, David S Cooper, Steven M Schwartz, Joshua W Salvin

Abstract readEvaluation StudyMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Critical care explorations, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sarah A TeeleDivision of Cardiovascular Critical Care Medicine, Department of Cardiology, Boston Children's Hospital, Boston, MA.
Avihu Z GazitDivision of Pediatric Cardiac Critical Care Medicine, Department of Critical Care Medicine, Pittsburgh Children's Hospital, Pittsburgh, PA.
Craig FuttermanDivision of Cardiac Critical Care Medicine, Department of Pediatrics, George Washington University, Children's National Hospital, Washington, DC.
William G La CavaComputational Health Informatics Program, Boston Children's Hospital, Boston, MA.
David S CooperDepartment of Pediatrics, University of Cincinnati College of Medicine, The Heart Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH.
Steven M SchwartzDivision of Cardiac Critical Care Medicine, Departments of Critical Care Medicine and Pediatrics, The Hospital for Sick Children and The University of Toronto Temerty Faculty of Medicine, Toronto, ON, Canada.
Joshua W SalvinDivision of Cardiovascular Critical Care Medicine, Department of Cardiology, Boston Children's Hospital, Boston, MA.

Funding

Risk-based Patient Monitoring for Pediatric Cardiac PatientsR44HL117340 · NHLBI · ETIOMETRY, LLC · PI BARONOV, DIMITAR VALERIEV, SALVIN, JOSHUA W. · 2015 to 2020
$5.0M
NHLBI NIH HHS R44 HL117340
6 · The paper itself

Abstract

backgroundAccurate assessment of oxygen delivery relative to oxygen demand is crucial in the care of a critically ill patient. The central venous oxygen saturation (Svo

objectiveThe predictive analytics algorithm, inadequate delivery of oxygen (IDo DERIVATION COHORT: A retrospective multicenter cohort study was conducted using data temporally independent from the design and development phase of the IDo VALIDATION COHORT: A total of 20,424 Svo PREDICTION MODEL: The ability of the IDo

resultsArea under the receiver operating characteristic curve (AUC) was calculated for each index threshold. Datasets with greater amounts of available data had larger AUC scores. This was observed across each configuration. For the majority of thresholds, Svo

conclusionsThe IDo

Indexed as

AlgorithmsCritical IllnessOxygenOxygen SaturationAdolescentChildChild, PreschoolFemaleHumansInfantInfant, NewbornMaleRetrospective StudiesRisk AssessmentROC CurveOxygencardiac outputcentral venous oxygen saturationcritical caremonitoringpediatricspredictive analytics

Identifiers

PMID39830836
PMCPMC11741213

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.