Evidence map›Paper›PMID 39830770›Full record

ArticleTranslational lung cancer research2024

A rationale for the poor response to alectinib in a patient with adenocarcinoma of the lung harbouring a

Massimo Barberis, Alessandra Rappa, Filippo de Marinis, Giuseppe Pelosi, Elena Guerini Rocco, Yinxiu Zhan, Guido Tiana

Abstract readCase Reports
In one paragraph

Article in Translational lung cancer research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. A Patient With NovelJTO clinical and research reports · 2026
    Article
  3. Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Massimo BarberisDepartment of Experimental Oncology, Istituto Europeo di Oncologia, IRCCS, Milano, Italy.ORCID https://orcid.org/0000-0002-0943-4804
Alessandra RappaDivision of Pathology, Istituto Europeo di Oncologia, IRCCS, Milano, Italy.
Filippo de MarinisDivision of Thoracic Oncology, Istituto Europeo di Oncologia, IRCCS, Milano, Italy.ORCID https://orcid.org/0000-0002-1118-5536
Giuseppe PelosiDepartment of Oncology and Hemato-Oncology, University of Milan, Milan, Italy.ORCID https://orcid.org/0000-0003-4725-4692
Elena Guerini RoccoDivision of Pathology, Istituto Europeo di Oncologia, IRCCS, Milano, Italy.ORCID https://orcid.org/0000-0003-2001-7582
Yinxiu ZhanDepartment of Experimental Oncology, Istituto Europeo di Oncologia, IRCCS, Milano, Italy.ORCID https://orcid.org/0000-0001-7702-6207
Guido TianaDepartment of Physics and Center for Complexity and Biosystems, Università degli Studi di Milano and INFN, Milano, Italy.ORCID https://orcid.org/0000-0002-5099-2592

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Non-small cell lung cancers (NSCLCs) with Case Description: Here we describe a case of a stage IV lung adenocarcinoma with a rare striatin Conclusions: Our model calculations suggested that the effect of the translocation was to induce the dimerization of

Indexed as

alectinibALK fusionartificial intelligence (AI)case reportSTRN-ALK

Identifiers

PMID39830770
PMCPMC11736610

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.