Evidence map›Paper›PMID 39830719›Full record

ArticleACS environmental Au2025

Slow-Release Pharmaceutical Implants in Ecotoxicology: Validating Functionality across Exposure Scenarios.

Michael G Bertram, Jack A Brand, Eli S J Thoré, Daniel Cerveny, Erin S McCallum, Marcus Michelangeli, Jake M Martin, Jerker Fick, Tomas Brodin

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS environmental Au, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Advancing the Spatiotemporal Dimension of Wildlife-Pollution Interactions.Environmental science & technology letters · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Michael G BertramDepartment of Wildlife, Fish, and Environmental Studies, Swedish University of Agricultural Sciences, Umeå SE-907 36, Sweden.ORCID https://orcid.org/0000-0001-5320-8444
Jack A BrandDepartment of Wildlife, Fish, and Environmental Studies, Swedish University of Agricultural Sciences, Umeå SE-907 36, Sweden.
Eli S J ThoréDepartment of Wildlife, Fish, and Environmental Studies, Swedish University of Agricultural Sciences, Umeå SE-907 36, Sweden.ORCID https://orcid.org/0000-0002-0029-8404
Daniel CervenyDepartment of Wildlife, Fish, and Environmental Studies, Swedish University of Agricultural Sciences, Umeå SE-907 36, Sweden.
Erin S McCallumDepartment of Wildlife, Fish, and Environmental Studies, Swedish University of Agricultural Sciences, Umeå SE-907 36, Sweden.ORCID https://orcid.org/0000-0001-5426-9652
Marcus MichelangeliDepartment of Wildlife, Fish, and Environmental Studies, Swedish University of Agricultural Sciences, Umeå SE-907 36, Sweden.
Jake M MartinDepartment of Wildlife, Fish, and Environmental Studies, Swedish University of Agricultural Sciences, Umeå SE-907 36, Sweden.
Jerker FickDepartment of Chemistry, Umeå University, Umeå 907 36, Sweden.ORCID https://orcid.org/0000-0002-3949-7371
Tomas BrodinDepartment of Wildlife, Fish, and Environmental Studies, Swedish University of Agricultural Sciences, Umeå SE-907 36, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pharmaceutical contaminants have spread in natural environments across the globe, endangering biodiversity, ecosystem functioning, and public health. Research on the environmental impacts of pharmaceuticals is growing rapidly, although a majority of studies are still conducted under controlled laboratory conditions. As such, there is an urgent need to understand the impacts of pharmaceutical exposures on wildlife in complex, real-world scenarios. Here, we validate the performance of slow-release pharmaceutical implants-a recently developed tool in field-based ecotoxicology that allows for the controlled chemical dosing of free-roaming aquatic species-in terms of the accumulation and distribution of pharmaceuticals of interest in tissues. Across two years, we directly exposed 256 Atlantic salmon (

Identifiers

PMID39830719
PMCPMC11741056

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.