Evidence map›Paper›PMID 39830684›Full record

ArticleRSC chemical biology2025

Siderophore-based targeted antibody recruitment for promoting immune responses towards Gram-negative pathogens.

Seungwoo Kim, Ho-Sung Park, Do Young Kim, Hyunhi Joh, Jiseok Oh, Dong Ho Kim, Min Ju Kang, Chul Hee Choi, Hak Joong Kim

Abstract read
In one paragraph

Article in RSC chemical biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Salinity stress tolerance inFrontiers in plant science · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Seungwoo KimDepartment of Chemistry and Center for Proteogenome Research Korea University Seoul 02841 Republic of Korea hakkim@korea.ac.kr.
Ho-Sung ParkDepartment of Microbiology and Medical Science Chungnam National University School of Medicine Daejeon 35015 Republic of Korea choich@cnu.ac.kr.
Do Young KimDepartment of Chemistry and Center for Proteogenome Research Korea University Seoul 02841 Republic of Korea hakkim@korea.ac.kr.ORCID https://orcid.org/0000-0002-0763-8408
Hyunhi JohDepartment of Chemistry and Center for Proteogenome Research Korea University Seoul 02841 Republic of Korea hakkim@korea.ac.kr.
Jiseok OhDepartment of Chemistry and Center for Proteogenome Research Korea University Seoul 02841 Republic of Korea hakkim@korea.ac.kr.
Dong Ho KimDepartment of Microbiology and Medical Science Chungnam National University School of Medicine Daejeon 35015 Republic of Korea choich@cnu.ac.kr.
Min Ju KangDepartment of Microbiology and Medical Science Chungnam National University School of Medicine Daejeon 35015 Republic of Korea choich@cnu.ac.kr.
Chul Hee ChoiDepartment of Microbiology and Medical Science Chungnam National University School of Medicine Daejeon 35015 Republic of Korea choich@cnu.ac.kr.
Hak Joong KimDepartment of Chemistry and Center for Proteogenome Research Korea University Seoul 02841 Republic of Korea hakkim@korea.ac.kr.ORCID https://orcid.org/0000-0002-3213-2230

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antibody-recruiting molecules (ARMs) have emerged as a promising strategy for enhancing immune responses against pathogens and cancer cells. In this study, we developed a novel class of antibacterial ARMs utilizing siderophores, small iron-chelating compounds, as targeting motifs. Siderophores naturally exhibit high specificity for bacterial pathogens due to their role in iron acquisition, making them ideal candidates for selective targeting. We identified a potent ARM, GNP3, comprising MECAM, a siderophore mimetic, and 2,4-dinitrophenyl (DNP), a motif recognized by endogenous antibodies, connected

Identifiers

PMID39830684
PMCPMC11740091

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.