Evidence map›Paper›PMID 39830672›Full record

ArticleIranian journal of pharmaceutical research : IJPR

Antiproliferative and Pro-apoptotic Activities of

Zoila Mora-Guzmán, Luis Bernardo Flores-Cotera, Eduardo Pérez-Campos, Rebeca López-Marure, Delia Soto-Castro, Felipe Alonso Masso-Rojas, Araceli Paéz Arenas, Edgar Zenteno, Margarito Martinez-Cruz, Laura Pérez-Campos Mayoral and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Iranian journal of pharmaceutical research : IJPR. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Zoila Mora-GuzmánUNAM-UABJO, Faculty of Medicine Research Center, Faculty of Medicine and Surgery, Autonomous University Benito Juarez of Oaxaca, Oaxaca, Mexico.
Luis Bernardo Flores-CoteraDepartment of Biotechnology and Bioengineering, Center for Research and Advanced Studies of the National Polytechnic Institute (Cinvestav-IPN), Oaxaca, Mexico.
Eduardo Pérez-CamposNational Institute of Technology of Mexico, Technological Institute of Oaxaca, Oaxaca, Mexico.
Rebeca López-MarureDepartment of Physiology, National Institute of Cardiology Ignacio Chávez, Mexico City, Mexico.
Delia Soto-CastroCONAHCYT, National Polytechnic Institute, CIIDIR Oaxaca Unit, Oaxaca, Mexico.
Felipe Alonso Masso-RojasTranslational Medicine Laboratory, UNAM-INC Unit, National Institute of Cardiology Ignacio Chávez, Mexico City, Mexico.
Araceli Paéz ArenasTranslational Medicine Laboratory, UNAM-INC Unit, National Institute of Cardiology Ignacio Chávez, Mexico City, Mexico.
Edgar ZentenoDepartment of Biochemistry, Faculty of Medicine, National Autonomous University of Mexico, Mexico City, Mexico.
Margarito Martinez-CruzNational Institute of Technology of Mexico, Technological Institute of Oaxaca, Oaxaca, Mexico.
Laura Pérez-Campos MayoralUNAM-UABJO, Faculty of Medicine Research Center, Faculty of Medicine and Surgery, Autonomous University Benito Juarez of Oaxaca, Oaxaca, Mexico.
María Teresa Hernández-HuertaCONAHCYT, Faculty of Medicine and Surgery, Autonomous University Benito Juarez of Oaxaca, Oaxaca, Mexico.ORCID https://orcid.org/0000-0003-2182-2540
María Del Socorro Pina-CansecoUNAM-UABJO, Faculty of Medicine Research Center, Faculty of Medicine and Surgery, Autonomous University Benito Juarez of Oaxaca, Oaxaca, Mexico.ORCID https://orcid.org/0000-0002-9486-5093

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Breast cancer is the most common cancer among women worldwide, impacting not only the patients but also their families and communities. Objectives: This study aims to evaluate the effects of the chloroformic extract of Methods: The effect of the extract on MCF-7 cell proliferation was measured using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) and crystal violet staining. Apoptosis was evaluated through fluorescein diacetate/propidium iodide staining and caspase-3, -6, and -9 activity assays. Results: The half-maximal inhibitory concentration (IC50) of the Conclusions:

Indexed as

AnticancerApoptosisBreast NeoplasmsMCF-7 CellsMedicinal PlantsPro-apoptotic

Identifiers

PMID39830672
PMCPMC11742378

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.