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ArticleClinical, cosmetic and investigational dentistry2025

Radiomorphometric Parameters in Mandibular Panoramic Radiographs of Hypothyroid Patients: A Cross-Sectional Study.

Ananya Nair, Vathsala Patil, Isha Bhardwaj, Deepak Kumar Singhal, Komal Smriti, Yogesh Chhaparwal, Shubha Chhaparwal, Disha Prabhu

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Article in Clinical, cosmetic and investigational dentistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Ananya Nair *Department of Oral Medicine and Radiology, Manipal College of Dental Sciences, Manipal, Manipal Academy of Higher Education, Manipal, Karnataka, 576104, India.
Vathsala Patil *Department of Oral Medicine and Radiology, Manipal College of Dental Sciences, Manipal, Manipal Academy of Higher Education, Manipal, Karnataka, 576104, India.ORCID 0000-0002-8656-8080
Isha Bhardwaj *Department of Oral Medicine and Radiology, Manipal College of Dental Sciences, Manipal, Manipal Academy of Higher Education, Manipal, Karnataka, 576104, India.
Deepak Kumar SinghalDepartment of Public Health Dentistry, Manipal College of Dental Sciences, Manipal, Manipal Academy of Higher Education, Manipal, Karnataka, 576104, India.
Komal SmritiDepartment of Oral Medicine and Radiology, Manipal College of Dental Sciences, Manipal, Manipal Academy of Higher Education, Manipal, Karnataka, 576104, India.
Yogesh ChhaparwalDepartment of Oral Medicine and Radiology, Manipal College of Dental Sciences, Manipal, Manipal Academy of Higher Education, Manipal, Karnataka, 576104, India.ORCID 0000-0003-0182-3183
Shubha ChhaparwalDepartment of Conservative Dentistry and Endodontics, Manipal College of Dental Sciences, Manipal, Manipal Academy of Higher Education, Manipal, Karnataka, 576104, India.
Disha PrabhuDepartment of Conservative Dentistry and Endodontics, Manipal College of Dental Sciences, Manipal, Manipal Academy of Higher Education, Manipal, Karnataka, 576104, India.ORCID 0009-0005-0628-2197

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Thyroid hormones have a catabolic effect on bone mineral homeostasis. Hypothyroid patients have shown changes in bone mineral density with increased risk for osteoporosis and bone fractures. Radiomorphometric parameters on panoramic images are good indicators of bone mineral density. The aim of the study was to compare the radiomorphometric parameters in dental panoramic images of patients diagnosed with hypothyroidism with age- and gender-matched control populations. Methods: Panoramic radiographs of 47 patients diagnosed with hypothyroidism were measured for radio morphometric indices like mental index (MI), The inferior panoramic mandibular index (PMI), antegonial index (AGI), gonial Index (GI) and mandibular cortical Index (MCI). The measurements were compared with age and gender matched 50 healthy controls. Results: The mean values of MI (3.11), PMI (0.28), and GI (1.38) were lower in hypothyroidism than in 50 healthy controls which was 3.17, 0.30 and 1.33, respectively. However, only AGI (3.14) showed statistically significant differences (p = 0.03). Conclusion: This study showed radiomorphometric parameters like MI, PMI, GI and AGI are valuable indicators of bone changes in mandible of patients with systemic diseases like hypothyroidism. Although statistically significant difference was seen only in AGI compared to healthy controls. Further studies with larger samples can provide substantial data. Applying newer technologies like machine learning can also help us determine whether mandibular morphometric parameters can predict changes in bone mineral density in hypothyroid cases.

Indexed as

bone mineral densityhypothyroidismosteoporosispanoramic radiographsradiomorphometric indices

Identifiers

PMID39830592
PMCPMC11742241

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