Evidence map›Paper›PMID 39830583›Full record

ArticleCureus2024

The Effect of Perineural Adjuvants on Superficial Parasternal Intercostal Plane Blocks in Cardiac Surgery: A Triple-Blinded Randomized Controlled Feasibility Trial.

Rawad I Hamzi, Scott R Coleman, Salvador Pena, Joni K Evans, Heidi Whiteside, Bryan E Marchant, Karuna Puttur Rajkumar, Wessley McKnight, Shelby Harris, Nataya S Disher and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Rawad I HamziDepartment of Anesthesiology, Wake Forest School of Medicine, Winston Salem, USA.
Scott R ColemanDepartment of Anesthesiology, Wake Forest School of Medicine, Winston Salem, USA.
Salvador PenaDepartment of Anesthesiology, Wake Forest School of Medicine, Winston Salem, USA.
Joni K EvansDepartment of Biostatistics and Data Science, Wake Forest School of Medicine, Winston Salem, USA.
Heidi WhitesideDepartment of Biostatistics and Data Science, Wake Forest School of Medicine, Winston Salem, USA.
Bryan E MarchantDepartment of Anesthesiology, Wake Forest School of Medicine, Winston Salem, USA.
Karuna Puttur RajkumarDepartment of Anesthesiology, Wake Forest School of Medicine, Winston Salem, USA.
Wessley McKnightDepartment of Anesthesiology, Wake Forest School of Medicine, Winston Salem, USA.
Shelby HarrisDepartment of Anesthesiology, Wake Forest School of Medicine, Winston Salem, USA.
Nataya S DisherDepartment of Anesthesiology, Wake Forest School of Medicine, Winston Salem, USA.
Anusha N SamantDepartment of Anesthesiology, Wake Forest School of Medicine, Winston Salem, USA.
Rohesh J FernandoDepartment of Anesthesiology, Wake Forest School of Medicine, Winston Salem, USA.

Funding

Wake Forest Clinical and Translational Science AwardUL1TR001420 · NCATS · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI ARD, JAMY D, FOLEY, KRISTIE L · 2015 to 2023
$32.3M
NCATS NIH HHS UL1 TR001420
6 · The paper itself

Abstract

Background and aim The study aimed to investigate the effect of adding perineural adjuvants, clonidine and dexamethasone, to local anesthetic in Superficial Parasternal Intercostal Plane (SPIP) blocks. It was designed as a prospective, randomized, triple-blinded, feasibility trial, conducted at a single-center university hospital. The participants included adult patients who were undergoing cardiac surgery via median sternotomy. Methodology Following skin closure, patients were randomized to receive either SPIP with 0.25% bupivacaine and 2.5 mcg/mL epinephrine (control group,

Indexed as

adjuvantanalgesiacardiac surgerymedian sternotomypain managementpecto-intercostal fascial plane blockpifbregional anesthesiaspipsuperficial parasternal intercostal plane

Identifiers

PMID39830583
PMCPMC11741686

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.