Evidence map›Paper›PMID 39830565›Full record

ArticleCureus2024

Successful Resection of Small Intestinal Stenosis After Treatment With an Immune Checkpoint Inhibitor for Metastatic Lung Cancer in the Small Intestine: A Case Report.

Ayako Shimada, Shinnosuke Ohnaka, Masanao Nakashima, Atsushi Nagai

Abstract readCase Reports
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ayako ShimadaDepartment of Respiratory Medicine, Shin-Yurigaoka General Hospital, Kanagawa, JPN.
Shinnosuke OhnakaDepartment of Respiratory Medicine, Shin-Yurigaoka General Hospital, Kanagawa, JPN.
Masanao NakashimaDepartment of Respiratory Medicine, Shin-Yurigaoka General Hospital, Kanagawa, JPN.
Atsushi NagaiDepartment of Respiratory Medicine, Shin-Yurigaoka General Hospital, Kanagawa, JPN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gastrointestinal (GI) metastases from lung cancer are relatively rare, and their management strategies and outcomes in the era of immune checkpoint inhibitors are unknown. A 59-year-old man with lung cancer was hospitalized. He presented with vomiting due to a small intestinal metastasis. The metastatic lesion reduced in size with pembrolizumab treatment. However, the patient could not feed orally and required continuous central venous nutrition. Following the recurrence of a catheter-related bloodstream infection, the patient underwent small intestinal resection and gastrojejunal bypass surgery. Surgical specimens from the site of intestinal stenosis showed tumor disappearance and inflammatory cell invasion. GI stenosis due to lung cancer metastasis can persist even after effective treatment with immune checkpoint inhibitors. Therefore, surgery for GI metastases should be considered as necessary.

Indexed as

gastrointestinal metastasisimmune checkpoint inhibitorslung cancerpembrolizumabsmall intestinal stenosis

Identifiers

PMID39830565
PMCPMC11739535

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.