Evidence map›Paper›PMID 39830540›Full record

ArticleCureus2024

Immune Reconstitution Inflammatory Syndrome-Induced Thrombocytopenia in a Patient With HIV and Coccidioidomycosis.

Anthea Cheng, Simon Lalehzarian, Hridya Harimohan, Melanie Khamlong, Stanley Kim, Leila Moosavi

Abstract readCase Reports
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Anthea ChengMedical School, American University of the Caribbean, Cupecoy, SXM.
Simon LalehzarianMedical School, American University of the Caribbean, Cupecoy, SXM.
Hridya HarimohanInternal Medicine, Kern Medical, Bakersfield, USA.
Melanie KhamlongInternal Medicine, Kern Medical, Bakersfield, USA.
Stanley KimDivision of Hematology/Oncology, Kern Medical, Bakersfield, USA.
Leila MoosaviInternal Medicine, Kern Medical, Bakersfield, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Highly active antiretroviral therapy (HAART) is imperative in managing human immunodeficiency virus (HIV) infections. HAART aims to inhibit viral replication and improve immunity. Antiretroviral therapy has led to significant improvement in CD4-T cell counts and reductions in viral load, leading to improved overall immune function, increased survival, and decreased frequency of opportunistic infections. Immune reconstitution inflammatory syndrome (IRIS) is defined by a hyperinflammatory immune response within six months of initial treatment with HAART. It is caused by dysregulated inflammatory immune responses against pathogens. Herein, we discuss a rare presentation of IRIS-induced thrombocytopenia in a 20-year-old Hispanic male patient.

Indexed as

autoimmune thrombocytopeniacoccidioidomycosishiv/aidsimmune reconstitution inflammatory syndromethrombocytopenia

Identifiers

PMID39830540
PMCPMC11742094

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.