ReviewFrontiers in pharmacology2024
Research progress on the synthesis process, detection method, pharmacological effects and application of glycocholic acid.
Review in Frontiers in pharmacology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Sex and social group altered the gut microbiome and fecal metabolome in the critically endangered Yangtze finless porpoise (Current zoology · 2026Article
- Characteristics of gut microbiota and metabolites in patients with ulcerative colitis with fatigue.World journal of gastroenterology · 2026Article
- Genetic mapping of lifespan and mitochondrial stress response inbioRxiv : the preprint server for biology · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: This review aims to summarize the research progress of glycocholic acid to promote its broader development and application. Methods: This article collects relevant literature from databases such as Science Direct, PubMed, Web of Science, Google Scholar and CNKI from the establishment to 2024, systematically organizing and analyzing aspects of glycocholic acid including its physicochemical properties, synthesis and extraction techniques, detection methods, pharmacological effects, mechanisms of action, clinical research, and application as an excipient. Results: Glycocholic acid, as a key conjugated component in bile acids, exhibits various pharmacological effects such as anti-inflammatory and antioxidant activities. Nevertheless, current research on glycocholic acid is insufficient, with synthesis techniques requiring improvement, limited application of detection technologies, and a need for in-depth exploration of its pharmacological mechanisms. Due to its amphiphilic molecular structure, glycocholic acid is primarily used as a pharmaceutical excipient. Conclusion: This review summarizes the existing research on glycocholic acid, indicating that future research should strengthen work in this field, including improving synthesis processes and enhancing the sensitivity of detection technologies, to provide a scientific basis for the development of new formulations and drug combinations, thereby promoting the advancement of traditional Chinese medicine.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.