Evidence map›Paper›PMID 39830225›Full record

ArticleDEN open2025

A comparative study benchmarking colon polyp with computer-aided detection (CADe) software.

Nikolaos Papachrysos, Pia Helén Smedsrud, Kim V Ånonsen, Tor Jan D Berstad, Håvard Espeland, Andreas Petlund, Per J Hedenström, Pål Halvorsen, Jonas Varkey, Hugo L Hammer and 2 more

Abstract read
In one paragraph

Article in DEN open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Nikolaos PapachrysosDepartment of Medicine, Geriatrics and Emergencies Division of Gastroenterology Sahlgrenska University Hospital/Östra Gothenburg Sweden.ORCID https://orcid.org/0000-0002-2372-2554
Pia Helén SmedsrudAugere Medical AS Oslo Norway.
Kim V ÅnonsenDepartment of Gastroenterology Oslo University Hospital Oslo Norway.
Tor Jan D BerstadAugere Medical AS Oslo Norway.
Håvard EspelandAugere Medical AS Oslo Norway.
Andreas PetlundAugere Medical AS Oslo Norway.
Per J HedenströmDepartment of Molecular and Clinical Medicine, Institute of Medicine University of Gothenburg Gothenburg Sweden.
Pål HalvorsenSimulaMet Oslo Norway.
Jonas VarkeyDepartment of Molecular and Clinical Medicine, Institute of Medicine University of Gothenburg Gothenburg Sweden.
Hugo L HammerSimulaMet Oslo Norway.
Michael A RieglerSimulaMet Oslo Norway.
Thomas de LangeDepartment of Molecular and Clinical Medicine, Institute of Medicine University of Gothenburg Gothenburg Sweden.ORCID https://orcid.org/0000-0003-3989-7487

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and aims: Computer-aided detection software (CADe) has shown promising results in real-time polyp detection, but a limited head-to-head comparison of the available CADe systems has been performed. Moreover, such systems have not been compared to endoscopists using standardized videos. This study aims to compare the performance of three CADe systems in detecting polyps, employing a novel standardized methodology. Methods: Videos from 300 colonoscopies conducted at Oslo University Hospital were analyzed. Short video clips (20-45 s) presenting normal mucosa or polyps were randomly selected. These videos were then streamed through each CADe system from Medtronic, Olympus, and Augere Medical. Each system featured diverse configurations, resulting in a total of six software settings. Sensitivity and false positivity (FP) were assessed by comparing the CADe systems to both the mean of the systems and pairwise between them. Furthermore, the systems' performance was compared to the performance of five endoscopists. Results: CADe systems' sensitivity ranged between 84.9% and 98.7%, with statistically significant differences observed between the systems, both in comparison to the mean and to each other. FP rates ranged between 1.2% and 5.6%, also differing statistically significantly between the systems. The CADe systems achieving the highest sensitivity also exhibited the highest FP. Statistically significant differences in the alert delay were observed between different CADe systems and endoscopists. Conclusions: This study highlights significant differences between commercially available CADe software regarding sensitivity and FP, but a superior performance compared to endoscopists. The software with the highest sensitivity also exhibited the highest FP, highlighting the need for further refinement.

Indexed as

artificial intelligenceCADecolon polypscolorectal cancerpolyp detection

Identifiers

PMID39830225
PMCPMC11742239

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.