Evidence map›Paper›PMID 39829944›Full record

ArticleDrug and alcohol dependence reports2024

Extended-release buprenorphine induction in opioid non-tolerant incarcerated individuals.

Michael S Gordon, Thomas R Blue, Frank J Vocci, Shannon G Mitchell, Kevin R Wenzel, Marc Fishman

Abstract read
In one paragraph

Article in Drug and alcohol dependence reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Michael S GordonFriends Research Institute, Inc., 1040 Park Avenue, Suite 103, Baltimore, MD 21201, United States.
Thomas R BlueFriends Research Institute, Inc., 1040 Park Avenue, Suite 103, Baltimore, MD 21201, United States.
Frank J VocciFriends Research Institute, Inc., 1040 Park Avenue, Suite 103, Baltimore, MD 21201, United States.
Shannon G MitchellFriends Research Institute, Inc., 1040 Park Avenue, Suite 103, Baltimore, MD 21201, United States.
Kevin R WenzelMaryland Treatment Centers, 3800 Frederick Ave, Baltimore, MD 21229, United States.
Marc FishmanMaryland Treatment Centers, 3800 Frederick Ave, Baltimore, MD 21229, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Buprenorphine maintenance treatment remains unavailable in most jails in the US. We provide data on a four-day rapid sublingual buprenorphine (SL-B) induction strategy followed by a weekly dose of extended-release injectable buprenorphine (XR-B) with incarcerated individuals with opioid use disorder (OUD) who were not opioid tolerant. Methods: Between October 2020 to April 2024, Results: Sixty-five individuals received SL-B dose induction from our team's medical staff, 53 (81.5 %) completed the four-day SL-B dose induction and received their first weekly XR‑B injection on day 5. Of the 65 individuals, 10 (15.38 %) participants reported AEs during the dosing period and/or in the week following the dosing period. All but one of the AEs were rated as mild. One participant experienced a serious adverse event in the week following dose induction. The study medical team determined that this was unlikely to be related to the intervention. Discussion: Overall, our study findings demonstrate the feasibility of implementing a four-day sublingual dose induction followed by a weekly XR-B injection with incarcerated individuals who are not opioid tolerant. This study provides important data to illustrate a dose induction strategy that might assist in reducing illicit diversion in jails, which is a main barrier to buprenorphine delivery cited by correctional administrators.

Indexed as

Extended-release injectable buprenorphineJailSublingual buprenorphine

Identifiers

PMID39829944
PMCPMC11740793

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.