Evidence map›Paper›PMID 39829902›Full record

ArticlebioRxiv : the preprint server for biology2025

Differential encoding of odor and place in mouse piriform and entorhinal cortex.

Wilson Mena, Keeley Baker, Alon Rubin, Shaun Kohli, Yun Yoo, Brice Bathellier, Yaniv Ziv, Shahab Rezaei-Mazinani, Alexander Fleischmann

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Wilson MenaDepartment of Neuroscience, Pasteur Institute, Paris, France.
Keeley BakerDepartment of Neuroscience and Carney Institute for Brain Science, Brown University, Providence, USA.
Alon RubinDepartment of Neurobiology, Weizmann Institute of Science, Rehovot, Israel.
Shaun KohliDepartment of Neuroscience and Carney Institute for Brain Science, Brown University, Providence, USA.
Yun YooDepartment of Neuroscience and Carney Institute for Brain Science, Brown University, Providence, USA.
Brice BathellierUniversité Paris Cité, Institut Pasteur, AP-HP, Inserm, Fondation Pour l'Audition, Institut de l'Audition, IHU reConnect, F-75012 Paris, France.
Yaniv ZivDepartment of Neurobiology, Weizmann Institute of Science, Rehovot, Israel.
Shahab Rezaei-MazinaniCenter for Interdisciplinary Research in Biology (CIRB), Collège de France, Université PSL, CNRS, INSERM, 75005 Paris, France.
Alexander FleischmannDepartment of Neuroscience and Carney Institute for Brain Science, Brown University, Providence, USA.

Funding

Odor Memory Traces in the Mouse Olfactory Cortex - SupplementR01DC017437 · NIDCD · BROWN UNIVERSITY · PI FLEISCHMANN, ALEXANDER · 2019 to 2023
$2.3M
Brain Science Compute ClusterS10OD025181 · OD · BROWN UNIVERSITY · PI SANES, JEROME N · 2019 to 2019
$600k
NIDCD NIH HHS R01 DC017437NIH HHS S10 OD025181
6 · The paper itself

Abstract

The integration of olfactory and spatial information is critical for guiding animal behavior. The lateral entorhinal cortex (LEC) is reciprocally interconnected with cortical areas for olfaction and the hippocampus and thus ideally positioned to encode odor-place associations. Here, we used mini-endoscopes to record neural activity in the mouse piriform cortex (PCx) and LEC. We show that in head-fixed mice, odor identity could be decoded from LEC ensembles, but less accurately than from PCx. In mice freely navigating a linear track, LEC ensemble activity at the odor ports was dominated by spatial information. Spatial position along the linear track could be decoded from LEC and PCx activity, however, PCx but not LEC exhibited strong behavior-driven modulation of positional information. Together, our data reveal that information about odor cues and spatial context is differentially encoded along the PCx-LEC axis.

Indexed as

lateral entorhinal cortexnavigationodor encodingolfactionpirifrom cortexplace encodingspatial information

Identifiers

PMID39829902
PMCPMC11741242

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.