Evidence map›Paper›PMID 39829784›Full record

ArticlebioRxiv : the preprint server for biology2025

Giant KASH proteins and ribosomes synergistically establish cytoplasmic biophysical properties

Xiangyi Ding, Hongyan Hao, Daniel Elnatan, Patrick Neo Alinaya, Shilpi Kalra, Abby Kaur, Sweta Kumari, Liam J Holt, G W Gant Luxton, Daniel A Starr

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Xiangyi DingDepartment of Molecular and Cellular Biology, University of California, Davis; Davis, CA, USA.
Hongyan HaoDepartment of Molecular and Cellular Biology, University of California, Davis; Davis, CA, USA.
Daniel ElnatanDepartment of Molecular and Cellular Biology, University of California, Davis; Davis, CA, USA.
Patrick Neo AlinayaDepartment of Molecular and Cellular Biology, University of California, Davis; Davis, CA, USA.
Shilpi KalraDepartment of Molecular and Cellular Biology, University of California, Davis; Davis, CA, USA.
Abby KaurDepartment of Molecular and Cellular Biology, University of California, Davis; Davis, CA, USA.
Sweta KumariDepartment of Molecular and Cellular Biology, University of California, Davis; Davis, CA, USA.
Liam J HoltDepartment of Biochemistry and Molecular Pharmacology, NYU Grossman School of Medicine; New Yor, NY, USA.
G W Gant LuxtonDepartment of Molecular and Cellular Biology, University of California, Davis; Davis, CA, USA.ORCID 0000-0002-6180-8906
Daniel A StarrDepartment of Molecular and Cellular Biology, University of California, Davis; Davis, CA, USA.ORCID 0000-0001-7339-6606

Funding

Mechanisms of Nuclear MigrationR35GM134859 · NIGMS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI DANIEL A STARR · 2020 to 2026
$2.8M
Tools to probe the biophysical properties of cellsR01GM132447 · NIGMS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI HOLT, LIAM J · 2019 to 2022
$2.1M
TorsinA-mediated regulation of Cdc42 signaling and DYT1 dystoniaR01GM129374 · NIGMS · UNIVERSITY OF MINNESOTA · PI LUXTON, GEORGE WILLIAM GANT · 2018 to 2021
$1.2M
NIGMS NIH HHS R01 GM129374NIGMS NIH HHS R01 GM132447NIGMS NIH HHS R35 GM134859
6 · The paper itself

Abstract

Understanding how cells control their biophysical properties during development remains a fundamental challenge. While cytoplasmic macromolecular crowding affects multiple cellular processes in single cells, its regulation in living animals remains poorly understood. Using genetically encoded multimeric nanoparticles for

Identifiers

PMID39829784
PMCPMC11741440

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.