Evidence map›Paper›PMID 39829759›Full record

ArticlebioRxiv : the preprint server for biology2025

The bile acid-sensitive ion channel is gated by Ca

Makayla M Freitas, Eric Gouaux

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Makayla M FreitasVollum Institute, Oregon Health and Science University, 3232 SW Research Drive, Portland, OR, USA.ORCID 0000-0002-8287-8428
Eric GouauxVollum Institute, Oregon Health and Science University, 3232 SW Research Drive, Portland, OR, USA.ORCID 0000-0002-8549-2360

Funding

Pacific Northwest Center for Cryo-EM: Equipment SupplementR24GM154185 · NIGMS · OREGON HEALTH & SCIENCE UNIVERSITY · PI James E Evans, CLAUDIA SUSANA LOPEZ · 2024 to 2026
$21.5M
3D STRUCTURE/FUNCTION OF LIGAND GATED ION CHANNELSR01NS038631 · NINDS · OREGON HEALTH & SCIENCE UNIVERSITY · PI GOUAUX, JAMES E · 1999 to 2024
$6.7M
The molecular architecture and mechanism of the Proton Activated Chloride (PAC) Channel.F31NS120713 · NINDS · OREGON HEALTH & SCIENCE UNIVERSITY · PI FREITAS, MAKAYLA · 2020 to 2021
$44k
NIGMS NIH HHS R24 GM154185NINDS NIH HHS F31 NS120713NINDS NIH HHS R01 NS038631
6 · The paper itself

Abstract

The bile acid-sensitive ion channel (BASIC) is the least understood member of the mammalian epithelial Na

Identifiers

PMID39829759
PMCPMC11741473

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.