Evidence map›Paper›PMID 39829737›Full record

ArticlebioRxiv : the preprint server for biology2025

Maturation of striatal dopamine supports the development of habitual behavior through adolescence.

Daniel J Petrie, Ashley C Parr, Valerie Sydnor, Amar Ojha, Will Foran, Brenden Tervo-Clemmens, Finnegan Calabro, Beatriz Luna

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Daniel J PetrieDepartment of Psychiatry, University of Pittsburgh, Pittsburgh, PA, 15213, United States.ORCID 0000-0002-5759-8037
Ashley C ParrDepartment of Psychiatry, University of Pittsburgh, Pittsburgh, PA, 15213, United States.
Valerie SydnorDepartment of Psychiatry, University of Pittsburgh, Pittsburgh, PA, 15213, United States.
Amar OjhaDepartment of Psychiatry, University of Pittsburgh, Pittsburgh, PA, 15213, United States.
Will ForanDepartment of Psychiatry, University of Pittsburgh, Pittsburgh, PA, 15213, United States.
Brenden Tervo-ClemmensDepartment of Psychiatry & Behavioral Sciences, University of Minnesota, Minneapolis, MN, 55454, United States.
Finnegan CalabroDepartment of Psychiatry, University of Pittsburgh, Pittsburgh, PA, 15213, United States.
Beatriz LunaDepartment of Psychiatry, University of Pittsburgh, Pittsburgh, PA, 15213, United States.

Funding

University of Pittsburgh Clinical and Translational Science InstituteUL1TR001857 · NCATS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI REIS, STEVEN E · 2016 to 2025
$129.3M
Refinement of Brain Mechanisms Underlying the Developmental Stabilization from Adolescent to Adult Neurocognitive ProcessingR01MH067924 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BEATRIZ LUNA · 2004 to 2026
$14.0M
Training for Transformative Discovery in PsychiatryT32MH016804 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI SWEET, ROBERT A · 1985 to 2025
$6.2M
Reward Processing in AdolescenceR01MH080243 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI LUNA, BEATRIZ · 2008 to 2019
$5.5M
INTERDISCIPLINARY ALCOHOL RESEARCH TRAINING PROGRAMT32AA007453 · NIAAA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BROOKE S.G. MOLINA · 1985 to 2026
$3.7M
NCATS NIH HHS UL1 TR001857NIAAA NIH HHS T32 AA007453NIMH NIH HHS R01 MH067924NIMH NIH HHS R01 MH080243NIMH NIH HHS T32 MH016804
6 · The paper itself

Abstract

Developmental trajectories during the transition from adolescence to adulthood contribute to the establishment of stable, adult forms of operation. Understanding the neural mechanisms underlying this transition is crucial for identifying variability in normal development and the onset of psychiatric disorders, which typically emerge during this time. Habitual behaviors can serve as a model for understanding brain mechanisms underlying the stabilization of adult behavior, while also conferring risk for psychopathologies. Dopaminergic (DA) processes in the basal ganglia are thought to facilitate the formation of habits; however, developmental trajectories of habits and the brain systems supporting them have not been characterized

Identifiers

PMID39829737
PMCPMC11741407

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.