In one paragraphArticle in Journal of neurophysiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
5 · Who and what moneyAuthors and funding
10 authors.
Khadijah ShanazzDepartment of Neuroscience and Regenerative Medicine, Medical College of Georgia, Augusta University, Augusta, Georgia, United States.ORCID 0000-0002-6556-0493 Kun XieDepartment of Physiology, Medical College of Georgia, Augusta University, Augusta, Georgia, United States.
Tucker OliverDepartment of Neurosurgery, Medical College of Georgia, Augusta University, Augusta, Georgia, United States.
Jamal BoganDepartment of Science and Mathematics, Augusta University, Augusta, Georgia, United States.ORCID 0009-0005-7699-1888 Fernando L ValeDepartment of Neurosurgery, Medical College of Georgia, Augusta University, Augusta, Georgia, United States.
Jeremy SwordDepartment of Neuroscience and Regenerative Medicine, Medical College of Georgia, Augusta University, Augusta, Georgia, United States.ORCID 0000-0001-7303-6010 Sergei A KirovDepartment of Neuroscience and Regenerative Medicine, Medical College of Georgia, Augusta University, Augusta, Georgia, United States.
Alvin TerryDepartment of Pharmacology and Toxicology, Medical College of Georgia, Augusta University, Augusta, Georgia, United States.ORCID 0000-0003-2071-4767 Philip O'HerronDepartment of Physiology, Medical College of Georgia, Augusta University, Augusta, Georgia, United States.ORCID 0000-0002-8137-9432 David T BlakeDepartment of Neuroscience and Regenerative Medicine, Medical College of Georgia, Augusta University, Augusta, Georgia, United States.
Funding
Primate model of deep brain stimulation for Alzheimers and age-related cognitivedeclineRF1AG060754 · NIA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI BLAKE, DAVID T, CONSTANTINIDIS, CHRISTOS · 2019 to 2019
$3.9MSynaptic Circuitry in StrokeR01NS083858 · NINDS · AUGUSTA UNIVERSITY · PI KIROV, SERGEI A · 2014 to 2022
$2.7MUncovering the physiological role of functional hyperemiaR01NS126920 · NINDS · AUGUSTA UNIVERSITY · PI Philip O'Herron · 2023 to 2026
$1.8MHHS | NIH | National Institute of Neurological Disorders and Stroke (NINDS) R01NS083858HHS | NIH | National Institute of Neurological Disorders and Stroke (NINDS) R01NS126920HHS | NIH | National Institute on Aging (NIA) RF1AG060754NIA NIH HHS RF1 AG060754NINDS NIH HHS R01 NS083858NINDS NIH HHS R01 NS126920
6 · The paper itselfAbstract
Deep brain stimulation (DBS) using electrical stimulation of neuronal tissue in the basal forebrain to enhance release of the neurotransmitter acetylcholine is under consideration to improve executive function in patients with dementia. Although some small studies indicate a positive response in the clinical setting, the relationship between DBS and acetylcholine pharmacokinetics is incompletely understood. We examined the cortical acetylcholine response to different stimulation parameters of the basal forebrain. Two-photon in vivo imaging was combined with deep brain stimulation in C57BL/6J mice. Stimulating electrodes were implanted in the subpallidal basal forebrain, and the ipsilateral somatosensory cortex was imaged. Acetylcholine activity was determined using the GRAB
Indexed as
AcetylcholineBasal ForebrainDeep Brain StimulationSomatosensory CortexAnimalsCholinesterase InhibitorsDonepezilMaleMiceMice, Inbred C57BLAcetylcholineCholinesterase InhibitorsDonepezilacetylcholinebasal forebraindonepezilGRAB ACH 3.0two-photon in vivo imaging
Identifiers
PMID39829107
PMCPMC12183691
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