ArticleThe Kaohsiung journal of medical sciences2025
Real-world efficacy and safety of universal 8-week glecaprevir/pibrentasvir in patients with chronic hepatitis C with early chronic kidney disease or pre-end-stage renal disease: Insights from a nationwide hepatisis C virus registry in Taiwan.
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Article in The Kaohsiung journal of medical sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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2citing papers in PubMed
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2 citing papers in PubMed.
- Effects of Sofosbuvir/Velpatasvir Therapy on Extrahepatic Manifestations in Patients With Type 2 Diabetes and Chronic Hepatitis C: Insights From a Nationwide Hepatitis C Virus Registry in Taiwan.The Kaohsiung journal of medical sciences · 2025Article
- Real-world efficacy and safety of universal 8-week glecaprevir/pibrentasvir in patients with chronic hepatitis C with early chronic kidney disease or pre-end-stage renal disease: Insights from a nationwide hepatisis C virus registry in Taiwan.The Kaohsiung journal of medical sciences · 2025Article
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Authors and funding
44 authors.
Szu-Jen WangGraduate Institute of Clinical Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.
Chung-Feng HuangHepatobiliary Division, Department of Internal Medicine and Hepatitis Center, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.
Te-Sheng ChangDivision of Hepatogastroenterology, Department of Internal Medicine, ChiaYi Chang Gung Memorial Hospital, Chiayi, Taiwan.
Ching-Chu LoDivision of Gastroenterology, Department of Internal Medicine, St. Martin De Porres Hospital, Chiayi, Taiwan.
Chao-Hung HungDivision of Hepatogastroenterology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan.
Chien-Wei HuangDivision of Gastroenterology, Kaohsiung Armed Forces General Hospital, Kaohsiung, Taiwan.
Lee-Won ChongDivision of Hepatology and Gastroenterology, Department of Internal Medicine, Shin Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan.
Pin-Nan ChengDivision of Gastroenterology and Hepatology, Department of Internal Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Ming-Lun YehHepatobiliary Division, Department of Internal Medicine and Hepatitis Center, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.
Cheng-Yuan PengCenters for Digestive Medicine, Department of Internal Medicine, China Medical University Hospital, Taichung, Taiwan.
Chien-Yu ChengDivision of Infectious Diseases, Department of Internal Medicine, Taoyuan General Hospital, Ministry of Health and Welfare, Taoyuan, Taiwan.
Jee-Fu HuangHepatobiliary Division, Department of Internal Medicine and Hepatitis Center, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.
Ming-Jong BairDivision of Gastroenterology, Department of Internal Medicine, Taitung Mackay Memorial Hospital, Taitung, Taiwan.
Chih-Lang LinLiver Research Unit, Department of Hepato Gastroenterology and Community Medicine Research Center, Chang Gung Memorial Hospital at Keelung, College of Medicine, Chang Gung University, Keelung, Taiwan.
Chi-Chieh YangDepartment of Gastroenterology, Division of Internal Medicine, Show Chwan Memorial Hospital, Changhua, Taiwan.
Hsing-Tao KuoDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Chi Mei Medical Center, Yongkang District, Tainan, Taiwan.
Tsai-Yuan HsiehDivision of Gastroenterology, Department of Internal Medicine, Tri Service General Hospital, National Defense Medical Center, Taipei, Taiwan.
Tzong-Hsi LeeDivision of Gastroenterology and Hepatology, Far Eastern Memorial Hospital, New Taipei City, Taiwan.
Pei-Lun LeeDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Chi Mei Medical Center, Tainan, Taiwan.
Wen-Chih WuWen-Chih Wu Clinic, Fengshan, Kaohsiung, Taiwan.
Chih-Lin LinDepartment of Gastroenterology, Renai Branch, Taipei City Hospital, Taipei, Taiwan.
Wei-Wen SuDepartment of Gastroenterology and Hepatology, Changhua Christian Hospital, Changhua, Taiwan.
Sheng-Shun YangDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan.
Chia-Chi WangTaipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation and School of Medicine, Tzu Chi University, Taipei, Taiwan.
Jui-Ting HuLiver Center, Cathay General Hospital, Taipei, Taiwan.
Lein-Ray MoDivision of Gastroenterology, Tainan Municipal Hospital (Managed By Show Chwan Medical Care Corporation), Tainan, Taiwan.
Chun-Ting ChenDivision of Gastroenterology, Department of Internal Medicine, Tri Service General Hospital, National Defense Medical Center, Taipei, Taiwan.
Yi-Hsiang HuangDivision of Gastroenterology and Hepatology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan.
Chun-Chao ChangDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Taipei Medical University Hospital, Taipei, Taiwan.
Chia-Sheng HuangYang Ming Hospital, Chiayi, Taiwan.
Guei-Ying ChenPenghu Hospital, Ministry of Health and Welfare, Taiwan.
Chien-Neng KaoNational Taiwan University Hospital Hsin-Chu Branch, Hsinchu, Taiwan.
Chi-Ming TaiDivision of Gastroenterology and Hepatology, Department of Internal Medicine, E-Da Hospital, I-Shou University, Kaohsiung, Taiwan.
Chun-Jen LiuHepatitis Research Center and Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.
Mei-Hsuan LeeInstitute of Clinical Medicine, National Yang-Ming Chiao Tung University, Taipei, Taiwan.
Pei-Chien TsaiHepatobiliary Division, Department of Internal Medicine and Hepatitis Center, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.
Chia-Yen DaiHepatobiliary Division, Department of Internal Medicine and Hepatitis Center, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.
Jia-Horng KaoHepatitis Research Center and Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.
Han-Chieh LinDivision of Gastroenterology and Hepatology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan.
Wang-Long ChuangHepatobiliary Division, Department of Internal Medicine and Hepatitis Center, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.
Kuo-Chih TsengSchool of Medicine, Tzuchi University, Hualien, Taiwan.
Chi-Yi ChenDivision of Gastroenterology and Hepatology, Department of Medicine, Ditmanson Medical Foundation Chiayi Christian Hospital, Chiayi, Taiwan.
Shu-Chi WangDepartment of Medical Laboratory Science and Biotechnology, Kaohsiung Medical University, Kaohsiung, Taiwan.
Ming-Lung YuHepatobiliary Division, Department of Internal Medicine and Hepatitis Center, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.ORCID https://orcid.org/0000-0001-8145-1900
Funding
Kaohsiung Medical University Chung-Ho Memorial Hospital 111004Kaohsiung Medical University Chung-Ho Memorial Hospital 111006Ministry of Education (MOE) in TaiwanMinistry of Health and Welfare, Taiwan 112-TDU-B-221-124007Ministry of Science and Technology, Taiwan 112-2321-B-001-006
Abstract
An 8-week regimen of glecaprevir/pibrentasvir is recommended for treatment-naïve patients with chronic hepatitis C (CHC). In alignment with the Taiwanese government's objective to eliminate hepatitis C by 2025, this study aimed to provide real-world evidence on the use of this regimen in treatment-naïve patients with chronic kidney disease (CKD) by using data from the Taiwan Association for the Study of the Liver HCV Registry (TACR). CKD was defined by an estimated glomerular filtration rate (eGFR) of <60 mL/min/1.73 m
Indexed as
Antiviral AgentsBenzimidazolesHepatitis C, ChronicKidney Failure, ChronicPyrrolidinesQuinoxalinesRenal Insufficiency, ChronicSulfonamidesAdultAgedAminoisobutyric AcidsCyclopropanesDrug CombinationsFemaleGlomerular Filtration RateHepacivirusAminoisobutyric AcidsAntiviral AgentsBenzimidazolesCyclopropanesDrug Combinationsglecaprevirglecaprevir and pibrentasvirLactams, MacrocyclicLeucinepibrentasvirProlinePyrrolidinesQuinoxalinesSulfonamideschronic hepatitis C (CHC)chronic kidney disease (CKD)direct‐acting antivirals (DAA)end‐stage renal disease (ESRD)real‐world
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.