Evidence map›Paper›PMID 39829087›Full record

ArticleImmunology2025

IL-6 Signalling to Responding T Cells Is Key to Calcitonin Gene-Related Peptide-Exposed Endothelial Cell Enhancement of Th17 Immunity During Langerhans Cell Antigen Presentation.

Wanhong Ding, Cameron Moattari, Lori L Stohl, John A Wagner, Xi K Zhou, Richard D Granstein

Abstract read
In one paragraph

Article in Immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Wanhong DingDepartment of Dermatology, Weill Cornell Medicine, New York, New York, USA.
Cameron MoattariDepartment of Dermatology, Weill Cornell Medicine, New York, New York, USA.
Lori L StohlDepartment of Dermatology, Weill Cornell Medicine, New York, New York, USA.
John A WagnerBrain and Mind Research Institute, Weill Cornell Medicine, New York, New York, USA.
Xi K ZhouDepartment of Population Health Sciences, Weill Cornell Medicine, New York, New York, USA.
Richard D GransteinDepartment of Dermatology, Weill Cornell Medicine, New York, New York, USA.ORCID 0000-0003-2824-7411

Funding

Clinical and Translational Science AwardUL1TR001873 · NCATS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI REILLY, MUREDACH P · 2016 to 2025
$99.0M
Disparities in COVID Disease Severity and Outcomes in New York CityUL1TR002384 · NCATS · WEILL MEDICAL COLL OF CORNELL UNIV · PI JULIANNE L IMPERATO-MCGINLEY · 2017 to 2026
$86.2M
Filomen M. D'Agostino FoundationNCATS NIH HHS UL1 TR001873NCATS NIH HHS UL1 TR002384PfizerSeth Sprague Educational and Charitable Foundation
6 · The paper itself

Abstract

Calcitonin gene-related peptide (CGRP) biases Langerhans cell (LC) Ag presentation to CD4

Indexed as

Antigen PresentationCalcitonin Gene-Related PeptideEndothelial CellsInterleukin-6Langerhans CellsTh17 CellsAnimalsCells, CulturedInterleukin-17MiceMice, Inbred C57BLMice, KnockoutReceptors, Interleukin-6Signal TransductionCalcitonin Gene-Related PeptideInterleukin-17Interleukin-6interleukin-6, mouseReceptors, Interleukin-6antigen presentation/processingcytokinesendothelial cellsneuroimmunology

Identifiers

PMID39829087
PMCPMC12135106

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.