Evidence map›Paper›PMID 39829022›Full record

ArticleJournal of proteome research2025

Detoxome Capacity of the Adult Rumen Fluke

Nathan Rhys Allen, Kathryn M Huson, Lukas Prchal, Mark W Robinson, Peter M Brophy, Russell M Morphew

Abstract read
In one paragraph

Article in Journal of proteome research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Nathan Rhys AllenDepartment of Life Sciences, Aberystwyth University, Aberystwyth, Wales SY23 3DA, U.K.
Kathryn M HusonSchool of Biological Sciences, Queen's University Belfast, Belfast, Northern Ireland BT9 5BY, U.K.
Lukas PrchalDepartment of Life Sciences, Aberystwyth University, Aberystwyth, Wales SY23 3DA, U.K.
Mark W RobinsonSchool of Biological Sciences, Queen's University Belfast, Belfast, Northern Ireland BT9 5BY, U.K.ORCID 0000-0001-7191-0034
Peter M BrophyDepartment of Life Sciences, Aberystwyth University, Aberystwyth, Wales SY23 3DA, U.K.ORCID 0000-0001-6363-1174
Russell M MorphewDepartment of Life Sciences, Aberystwyth University, Aberystwyth, Wales SY23 3DA, U.K.ORCID 0000-0003-0304-4730

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Helminth parasites have long adapted to survive hostile host environments and can likely adapt against the chemical anthelmintic challenge. One proposed adaptation route is via Phase I and II xenobiotic metabolizing enzymes (XMEs). For successful Helminth pharmacotherapy discovery programs, a working understanding of Helminth-derived chemical detoxification, the Helminth detoxome, is a must. At present, the detoxome of a newly emerging Helminth parasite, the rumen fluke

Indexed as

Extracellular VesiclesRumenAnimalsGene Expression ProfilingGlutathione TransferaseHelminth ProteinsInactivation, MetabolicParamphistomatidaeProteomeProteomicsSulfotransferasesGlutathione TransferaseHelminth ProteinsProteomeSulfotransferasesanthelminticdetoxomeextracellular vesicleglutathione transferaseHelminthrumen fluke

Identifiers

PMID39829022
PMCPMC11812014

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.