Evidence map›Paper›PMID 39829005›Full record

ArticleJournal of the American Chemical Society2025

C2-Selective Palladium-Catalyzed C-S Cross-Coupling of 2,4-Dihalopyrimidines.

Oliver D Jackson, Albert Reyes, Collin D Stein, Nathaniel G Larson, Calvin T Andrews, Sharon R Neufeldt

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Inverting the Conventional Site Selectivity of Cross-Coupling of 2,4-Dichloropyrimidines.Synlett : accounts and rapid communications in synthetic organic chemistry · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Oliver D JacksonDepartment of Chemistry and Biochemistry, Montana State University, Bozeman, Montana 59717, United States.ORCID 0000-0003-3817-7496
Albert ReyesDepartment of Chemistry and Biochemistry, Montana State University, Bozeman, Montana 59717, United States.ORCID 0000-0001-8944-6444
Collin D SteinDepartment of Chemistry and Biochemistry, Montana State University, Bozeman, Montana 59717, United States.ORCID 0009-0005-5492-8589
Nathaniel G LarsonDepartment of Chemistry and Biochemistry, Montana State University, Bozeman, Montana 59717, United States.ORCID 0000-0002-7631-3332
Calvin T AndrewsDepartment of Chemistry and Biochemistry, Montana State University, Bozeman, Montana 59717, United States.ORCID 0009-0002-8264-1786
Sharon R NeufeldtDepartment of Chemistry and Biochemistry, Montana State University, Bozeman, Montana 59717, United States.ORCID 0000-0001-7995-3995

Funding

Research Core (Developmental Research Project Program)P20GM103474 · NIGMS · MONTANA STATE UNIVERSITY - BOZEMAN · PI Ann Therese Bertagnolli · 2012 to 2026
$60.0M
Wyoming INBRE Phase 4- Equipment Supplement for x-ray diffractometer for Center for Advanced Scientific InstrumentationP20GM103432 · NIGMS · UNIVERSITY OF WYOMING · PI Nicolas A. Blouin · 2012 to 2026
$56.8M
Surveillance genome sequencing to detect SARS-CoV-2 virus variants in MontanaP30GM140963 · NIGMS · UNIVERSITY OF MONTANA · PI BOWLER, BRUCE E · 2021 to 2025
$6.9M
Supplement: Improving Small Molecule Synthesis by Controlling Reactions between Transition Metals and Carbon-Heteroatom ElectrophilesR35GM137971 · NIGMS · MONTANA STATE UNIVERSITY - BOZEMAN · PI Sharon Neufeldt · 2020 to 2026
$2.2M
Ultra Performance Liquid Chromatography Tandem Mass Spectrometer for MetabolomicsS10OD028650 · OD · MONTANA STATE UNIVERSITY - BOZEMAN · PI BOTHNER, BRIAN P · 2020 to 2020
$599k
NIGMS NIH HHS P20 GM103432NIGMS NIH HHS P20 GM103474NIGMS NIH HHS P30 GM140963NIGMS NIH HHS R35 GM137971NIH HHS S10 OD028650
6 · The paper itself

Abstract

Under most conditions, 2,4-dihalopyrimidines undergo substitution reactions at C4. Here we report that Pd(II) precatalysts supported by bulky

Identifiers

PMID39829005
PMCPMC11779575

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.