Evidence map›Paper›PMID 39828905›Full record

ArticleInnate immunity

Association of killer immunoglobulin-like receptor genotypes and haplotypes with acute lymphoblastic leukemia risk.

Jameel Al-Tamimi, Suliman Alomar, Ali Aljuaimlani, Lamjed Mansour

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Innate immunity. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. The Role of Killer Ig-like Receptors in Diseases from A to Z.International journal of molecular sciences · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jameel Al-TamimiDepartment of Zoology, College of Science, King Saud University, Riyadh, Saudi Arabia.
Suliman AlomarDepartment of Zoology, College of Science, King Saud University, Riyadh, Saudi Arabia.
Ali AljuaimlaniDepartment of Zoology, College of Science, King Saud University, Riyadh, Saudi Arabia.
Lamjed MansourDepartment of Zoology, College of Science, King Saud University, Riyadh, Saudi Arabia.ORCID 0000-0002-9415-9383

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundKiller immunoglobulin-like receptors (KIRs) are key molecules used by natural killer (NK) cells to interact with target cells. These receptors exhibit extensive genotypic polymorphism which has been associated with varying outcomes in immune responses against diseases. This study aimed to investigate the relationships between

methodsA total of 259 Saudi subjects including 145 cases of acute lymphoblastic leukemia (ALL) and 114 healthy controls living in Riyadh were genotyped for 16

resultsA significant high frequency of the two inhibitory

conclusionThis study presents strong evidence supporting the connection between certain

Indexed as

Killer Cells, NaturalPrecursor Cell Lymphoblastic Leukemia-LymphomaReceptors, KIRAdolescentAdultCase-Control StudiesChildChild, PreschoolFemaleGene FrequencyGenetic Association StudiesGenetic Predisposition to DiseaseGenotypeHaplotypesHLA-C AntigensHumansHLA-C AntigensReceptors, KIRacute lymphoblastic leukemiaHLA-C polymorphismKIR genotypeNatural killer cellsSaudi Arabia

Identifiers

PMID39828905
PMCPMC11774482

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.