Evidence map›Paper›PMID 39828809›Full record

ArticlePediatric cardiology2026

Valve Frame Geometry and Arrhythmia Risk Following Self-Expanding Transcatheter Pulmonary Valve Replacement.

Natalie Soszyn, Gabriel Yuen, Salvador R Franco, Johannes C von Alvensleben, Gareth J Morgan, Jenny E Zablah

Abstract read
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Article in Pediatric cardiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Natalie SoszynSchool of Medicine, Children's Hospital Colorado, The Heart Institute, University of Colorado Denver|Anschutz Medical Campus, 13123 E 16Th Ave, Box 100, Aurora, CO, 80045-2560, USA.
Gabriel YuenThe Heart Institute, Children's Hospital Colorado, 13123 E 16Th Ave, Box 100, Aurora, CO, 80045-2560, USA.
Salvador R FrancoThe Heart Institute, Children's Hospital Colorado, 13123 E 16Th Ave, Box 100, Aurora, CO, 80045-2560, USA.
Johannes C von AlvenslebenSchool of Medicine, Children's Hospital Colorado, The Heart Institute, University of Colorado Denver|Anschutz Medical Campus, 13123 E 16Th Ave, Box 100, Aurora, CO, 80045-2560, USA.
Gareth J MorganSchool of Medicine, Children's Hospital Colorado, The Heart Institute, University of Colorado Denver|Anschutz Medical Campus, 13123 E 16Th Ave, Box 100, Aurora, CO, 80045-2560, USA.
Jenny E ZablahSchool of Medicine, Children's Hospital Colorado, The Heart Institute, University of Colorado Denver|Anschutz Medical Campus, 13123 E 16Th Ave, Box 100, Aurora, CO, 80045-2560, USA. jenny.zablah@childrenscolorado.org.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Though major complications during transcutaneous pulmonary valve replacement (TPVR) are rare, clinically-significant ventricular arrythmia (CSVA) has been reported following self-expanding valve placement. We assess whether alterations in valve frame dimensions and geometry within the right ventricular outflow tract (RVOT) post-implantation in patients who underwent TPVR with Harmony TPV25 or Alterra contribute to CSVA risk. A single center review was performed of patients who underwent TPVR with either Harmony TPV25 or Alterra Pre-stent between August 2019 and April 2023. Using post-procedural 3D rotational acquisitions, minimum and maximum diameters were measured at 5 locations along the valve frame and perimeter and cross-sectional area (CSA) were measured closest to the pulmonary artery bifurcation and right ventricular (RV) cavity. To assess the relationship between the RVOT and valve frame, a RVOT-to-valve frame ratio together with percentage expansion, circularity and expansion ratios, and eccentricity indices were calculated. Twenty-eight patients were included (14 Harmony TPV25, 14 Alterra pre-stent). CSVA was seen more often in patients with congenital pulmonary stenosis (p = 0.02). CSVA was associated with a larger mean valve frame perimeter (118.3 vs 108.6 mm, p = 0.03) and CSA (1124.5 vs 926.2mm

Indexed as

Arrhythmias, CardiacCardiac CatheterizationHeart Valve ProsthesisHeart Valve Prosthesis ImplantationPostoperative ComplicationsPulmonary ValvePulmonary Valve InsufficiencyPulmonary Valve StenosisAdolescentChildChild, PreschoolFemaleHumansMaleProsthesis DesignRetrospective StudiesAlterraArrythmiaHarmonySelf-expandingTranscatheter pulmonary valve replacementValve geometry

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.