Evidence map›Paper›PMID 39827873›Full record

ArticleDigestive surgery2025

Procalcitonin as an Early Predictive Marker for Infectious Complications after Hepatectomy.

Haruki Mori, Hiromitsu Maehira, Nobuhito Nitta, Takeru Maekawa, Hajime Ishikawa, Katsushi Takebayashi, Sachiko Kaida, Toru Miyake, Masaji Tani

Abstract read
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Article in Digestive surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Haruki MoriDepartment of Surgery, Shiga University of Medical Science, Shiga, Japan, hmori@belle.shiga-med.ac.jp.
Hiromitsu MaehiraDepartment of Surgery, Shiga University of Medical Science, Shiga, Japan.
Nobuhito NittaDepartment of Surgery, Shiga University of Medical Science, Shiga, Japan.
Takeru MaekawaDepartment of Surgery, Shiga University of Medical Science, Shiga, Japan.
Hajime IshikawaDepartment of Surgery, Shiga University of Medical Science, Shiga, Japan.
Katsushi TakebayashiDepartment of Surgery, Shiga University of Medical Science, Shiga, Japan.
Sachiko KaidaDepartment of Surgery, Shiga University of Medical Science, Shiga, Japan.
Toru MiyakeDepartment of Surgery, Shiga University of Medical Science, Shiga, Japan.
Masaji TaniDepartment of Surgery, Shiga University of Medical Science, Shiga, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe present study aimed to determine the clinical value of serum procalcitonin (PCT) level in predicting postoperative infections after hepatectomy.

methodsMedical records of 301 consecutive patients who underwent hepatectomy were retrospectively reviewed. We divided the patients into infection-positive and infection-negative groups. We investigated the changes in perioperative inflammatory markers such as C-reactive protein level (CRP) and PCT level. Associations between infectious complications and perioperative inflammatory markers were evaluated to identify predictive factors of infectious complications after hepatectomy.

resultsPostoperative infectious complications occurred in 67 (22.3%) patients. The areas under the curve (AUCs) using PCT levels on postoperative days (PODs) 1 and 3 were 0.794 and 0.845, respectively, whereas those using CRP were 0.493 and 0.641, respectively. PCT level had a better AUC than CRP for predicting postoperative infectious complications on PODs 1 and 3. Multivariate analysis indicated PCT levels on PODs 1 and 3 were an independent predictor of infectious complications after hepatectomy.

conclusionPCT is the only predictive marker for infectious complications after hepatectomy and is valuable for detecting infectious complications from POD 1.

introductionThe present study aimed to determine the clinical value of serum procalcitonin (PCT) level in predicting postoperative infections after hepatectomy.

methodsMedical records of 301 consecutive patients who underwent hepatectomy were retrospectively reviewed. We divided the patients into infection-positive and infection-negative groups. We investigated the changes in perioperative inflammatory markers such as C-reactive protein level (CRP) and PCT level. Associations between infectious complications and perioperative inflammatory markers were evaluated to identify predictive factors of infectious complications after hepatectomy.

resultsPostoperative infectious complications occurred in 67 (22.3%) patients. The areas under the curve (AUCs) using PCT levels on postoperative days (PODs) 1 and 3 were 0.794 and 0.845, respectively, whereas those using CRP were 0.493 and 0.641, respectively. PCT level had a better AUC than CRP for predicting postoperative infectious complications on PODs 1 and 3. Multivariate analysis indicated PCT levels on PODs 1 and 3 were an independent predictor of infectious complications after hepatectomy.

conclusionPCT is the only predictive marker for infectious complications after hepatectomy and is valuable for detecting infectious complications from POD 1.

Indexed as

HepatectomyPostoperative ComplicationsProcalcitoninSurgical Wound InfectionAdultAgedArea Under CurveBiomarkersC-Reactive ProteinFemaleHumansMaleMiddle AgedPredictive Value of TestsRetrospective StudiesROC CurveBiomarkersC-Reactive ProteinProcalcitoninC-reactive proteinEarly detectionHepatectomyPostoperative infectious complicationProcalcitonin

Identifiers

PMID39827873
PMCPMC11887988

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.