Evidence map›Paper›PMID 39827619›Full record

ArticleCancer epidemiology2025

County socioeconomic status and premature mortality from cancer in the United States.

Aleah L Thomas, Rachel J Kulchar, Erica S Stephens, Lee Mason, Sarah S Jackson, Alexandra R Harris, Aldenise P Ewing, Meredith S Shiels, Catherine M Pichardo, Jennifer K McGee-Avila and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancer epidemiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Severe housing cost burden and premature cardiovascular mortality.American journal of preventive cardiology · 2025
    Article
  3. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Aleah L ThomasDivision of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, MD, United States; Weill Cornell Medicine, New York, NY, United States. Electronic address: alt4020@med.cornell.edu.
Rachel J KulcharSalivary Disorders Unit, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD, United States; School of Dentistry, University of California Los Angeles, Los Angeles, CA, United States.
Erica S StephensDivision of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, MD, United States.
Lee MasonDivision of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, MD, United States.
Sarah S JacksonDivision of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, MD, United States.
Alexandra R HarrisDivision of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, MD, United States.
Aldenise P EwingDivision of Epidemiology, College of Public Health, The Ohio State University, Columbus, OH, United States.
Meredith S ShielsDivision of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, MD, United States.
Catherine M PichardoDivision of Cancer Control and Population Sciences, NCI, NIH, Rockville, MD, United States.
Jennifer K McGee-AvilaDivision of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, MD, United States.
Wayne R LawrenceDivision of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, MD, United States.

Funding

Advancing Equity in Cancer Care: Investigating Health- Related Social Needs and Colonoscopy Follow-Up Among FQHC PatientsR01CA278052 · NCI · OHIO STATE UNIVERSITY · PI DOUGLAS Allen CORLEY, Chyke Abadama Doubeni · 2023 to 2026
$3.1M
Intramural NIH HHS Z99 CA999999NCI NIH HHS R01 CA278052NCI NIH HHS Y99 CA999999
6 · The paper itself

Abstract

introductionThere are consistent data demonstrating socioeconomic status (SES) is associated with cancer survivorship among older adults, but research on the relationship between area-level SES and risk of premature mortality from cancer remains not well understood. This study investigated the association between county-level SES and premature mortality from cancer.

methodsDemographic characteristics and causes of death were ascertained from the national death certificate data for years 2016-2020. Premature cancer death was defined as cancer mortality between ages 25-64. County SES was calculated using the Yost Index and categorized into distribution-based quintiles (1 =lowest SES, 5=highest SES). To calculate the mortality-adjusted rate ratios (aRR) and corresponding 95 % confidence intervals (95 %CI) for the associations between county SES and cancer, we performed multivariable linear mixed models, adjusting for confounders.

resultsA total of 3143 counties were included. The age-adjusted mortality rates of all cancers combined were 107.6, 98.4, 88.6, 81.1, and 66.7 per 100,000 population for the 5 SES quintiles, respectively. Compared with high SES counties, low SES counties had a 58 % greater premature cancer mortality rate (aRR

conclusionOur findings demonstrate that lower SES counties are at greater risk of premature mortality from cancer. Place-based interventions should target the socioeconomic environment across the cancer control continuum.

Indexed as

Mortality, PrematureNeoplasmsSocial ClassAdultCause of DeathFemaleHumansMaleMiddle AgedUnited StatesCancer mortalityPremature mortalitySocioeconomic status

Identifiers

PMID39827619
PMCPMC11890931

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.