Evidence map›Paper›PMID 39827470›Full record

ArticleAnalytical chemistry2025

Untargeted Swab Touch Spray-Mass Spectrometry Analysis with Machine Learning for On-Site Breast Surgical Margin Assessment.

Laura Min Xuan Chai, Ching Kao, Ming-Yang Wang, Cheng-Chih Hsu

Abstract read
In one paragraph

Article in Analytical chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Laura Min Xuan ChaiDepartment of Chemistry, National Taiwan University, Taipei 10617, Taiwan.ORCID 0000-0001-8713-3444
Ching KaoDepartment of Surgical Oncology, National Taiwan University Cancer Center, Taipei 10672, Taiwan.
Ming-Yang WangDepartment of Surgical Oncology, National Taiwan University Cancer Center, Taipei 10672, Taiwan.
Cheng-Chih HsuDepartment of Chemistry, National Taiwan University, Taipei 10617, Taiwan.ORCID 0000-0002-2892-5326

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Direct sampling mass spectrometry (MS) has rapidly advanced with the development of ambient ionization MS techniques. Swab touch-spray (TS)-MS has shown promise for rapid clinical diagnostics. However, commercially available swabs are notorious for their high background signals, particularly in the positive ionization mode. Although changes to MS methods or precleaning of the swabs can serve as workarounds, this inherent issue still limits the clinical application of swab TS-MS. In this study, we report the use of the sterile-packaged OmniSwab as an alternative material for untargeted swab TS-MS analysis. As a proof of concept, breast surgical margins were swabbed

Indexed as

BreastBreast NeoplasmsMachine LearningMargins of ExcisionMass SpectrometryFemaleHumans

Identifiers

PMID39827470
PMCPMC11800181

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.