Evidence map›Paper›PMID 39827403›Full record

ReviewNucleus (Austin, Tex.)2025

Nuclear envelope components in vascular mechanotransduction: emerging roles in vascular health and disease.

Tung D Nguyen, Michael A Winek, Mihir K Rao, Shaiva P Dhyani, Monica Y Lee

Abstract readReview
In one paragraph

Review in Nucleus (Austin, Tex.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Tung D NguyenDepartment of Physiology and Biophysics, The University of Illinois at Chicago - College of Medicine, Chicago, IL, USA.ORCID 0000-0001-5734-7011
Michael A WinekDepartment of Physiology and Biophysics, The University of Illinois at Chicago - College of Medicine, Chicago, IL, USA.ORCID 0000-0002-8620-2046
Mihir K RaoDepartment of Physiology and Biophysics, The University of Illinois at Chicago - College of Medicine, Chicago, IL, USA.
Shaiva P DhyaniDepartment of Physiology and Biophysics, The University of Illinois at Chicago - College of Medicine, Chicago, IL, USA.
Monica Y LeeDepartment of Physiology and Biophysics, The University of Illinois at Chicago - College of Medicine, Chicago, IL, USA.ORCID 0000-0002-7206-5562

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The vascular network, uniquely sensitive to mechanical changes, translates biophysical forces into biochemical signals for vessel function. This process relies on the cell's architectural integrity, enabling uniform responses to physical stimuli. Recently, the nuclear envelope (NE) has emerged as a key regulator of vascular cell function. Studies implicate nucleoskeletal elements (

Indexed as

Cardiovascular DiseasesMechanotransduction, CellularNuclear EnvelopeVascular DiseasesAnimalsCytoskeletonHumansCardiovascular diseaseendothelial cellsLINC complexnuclear laminanuclear pore complexvascular smooth muscle cells

Identifiers

PMID39827403
PMCPMC12710930

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.