Evidence map›Paper›PMID 39827282›Full record

ArticleScientific reports2025

Association of chronic stress during studies with depressive symptoms 10 years later.

Tobias Weinmann, Razan Wibowo, Felix Forster, Jessica Gerlich, Laura Wengenroth, Gudrun Weinmayr, Jon Genuneit, Dennis Nowak, Christian Vogelberg, Katja Radon and 1 more

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Tobias WeinmannInstitute and Clinic for Occupational, Social and Environmental Medicine, LMU University Hospital, LMU Munich, Ziemssenstr. 5, 80336, Munich, Germany. tobias.weinmann@med.lmu.de.ORCID 0000-0002-4582-5191
Razan WibowoInstitute and Clinic for Occupational, Social and Environmental Medicine, LMU University Hospital, LMU Munich, Ziemssenstr. 5, 80336, Munich, Germany.ORCID 0000-0002-7524-9973
Felix ForsterInstitute and Clinic for Occupational, Social and Environmental Medicine, LMU University Hospital, LMU Munich, Ziemssenstr. 5, 80336, Munich, Germany.ORCID 0000-0002-3670-9244
Jessica GerlichInstitute and Clinic for Occupational, Social and Environmental Medicine, LMU University Hospital, LMU Munich, Ziemssenstr. 5, 80336, Munich, Germany.
Laura WengenrothInstitute and Clinic for Occupational, Social and Environmental Medicine, LMU University Hospital, LMU Munich, Ziemssenstr. 5, 80336, Munich, Germany.ORCID 0000-0003-4730-1612
Gudrun WeinmayrInstitute of Epidemiology and Medical Biometry, Ulm University, Ulm, Germany.
Jon GenuneitInstitute of Epidemiology and Medical Biometry, Ulm University, Ulm, Germany.
Dennis NowakInstitute and Clinic for Occupational, Social and Environmental Medicine, LMU University Hospital, LMU Munich, Ziemssenstr. 5, 80336, Munich, Germany.ORCID 0000-0001-7871-8686
Christian VogelbergDepartment of Pediatrics, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.ORCID 0000-0002-4881-8368
Katja RadonInstitute and Clinic for Occupational, Social and Environmental Medicine, LMU University Hospital, LMU Munich, Ziemssenstr. 5, 80336, Munich, Germany.
Britta HerbigInstitute and Clinic for Occupational, Social and Environmental Medicine, LMU University Hospital, LMU Munich, Ziemssenstr. 5, 80336, Munich, Germany.ORCID 0000-0002-6772-5255

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The long-tern implications of stress during university for individuals' mental health are not well understood so far. Hence, we aimed to examine the potential effect of stress while studying at university on depression in later life. We analysed data from two waves of the longitudinal Study on Occupational Allergy Risks. Using the 'work overload' and 'proving oneself' scales of the Trier Inventory for Chronic Stress and the Patient Health Questionnaire-2 (PHQ-2), participants reported chronic stress during university (2007-2009, mean age 22.2 years, T1) and depressive symptoms ten years later (2017-2018, mean age 31.6 years, T2). We performed linear regression analyses to explore the association between stress during university (T1) and later depressive symptoms (T2). Participants (N = 548, 59% female) indicated rather low levels of stress and depression (PHQ-2 mean score: 1.14 (range: 0-6)). We observed evidence for a linear association between overload at T1 and depression at T2 (regression coefficient (B) = 0.270; 95% confidence interval (CI) = 0.131 to 0.409; standardised regression coefficient (β) = 0.170). Our analyses yielded evidence for an association between chronic stress while studying and risk of depressive symptoms later in life. This finding underlines the importance of implementing sustainable preventive measures against stress among students.

Indexed as

DepressionStress, PsychologicalStudentsAdultChronic DiseaseFemaleHumansLongitudinal StudiesMaleRisk FactorsSurveys and QuestionnairesUniversitiesYoung AdultChronic stressDepressionMental healthPsychological stressStudents

Identifiers

PMID39827282
PMCPMC11742973

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.