Evidence map›Paper›PMID 39827250›Full record

ArticleMolecular neurobiology2025

Characterizing Genetic-Predisposed Proteins Involving Insomnia by Integrating Genome-Wide Association Study Summary Statistics.

Jiang Long, Meng Dou, Xiangdong Tang, Xiaojing Gu

Abstract read
In one paragraph

Article in Molecular neurobiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jiang LongMental Health Center, West China Hospital, Sichuan University, Chengdu, China.
Meng DouInstitute of Computer Application, Chinese Academy of Sciences, Chengdu, Sichuan, China.
Xiangdong TangMental Health Center, West China Hospital, Sichuan University, Chengdu, China. 2372564613@qq.com.
Xiaojing GuMental Health Center, West China Hospital, Sichuan University, Chengdu, China. guxiaojing@wchscu.cn.

Funding

Ministry of Science and Technology of the People's Republic of China 2021ZD0201900National Natural Science Foundation of China 82120108002 and U21A20335National Natural Science Foundation of China 82301711
6 · The paper itself

Abstract

Large case-control genome-wide association studies (GWASs) have detected loci associated with insomnia, but how these risk loci confer disease risk remains largely unknown. By integrating brain protein quantitative trait loci (pQTL) (N

Indexed as

Genetic Predisposition to DiseaseGenome-Wide Association StudySleep Initiation and Maintenance DisordersHumansMendelian Randomization AnalysisQuantitative Trait LociGenome-wide association studyInsomniaMendelian randomizationProteins

Identifiers

PMID39827250
PMCPMC11953091

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.