ArticleEye (London, England)2025
Incidence of optic nerve kinking in a cohort of patients with Normal tension glaucoma.
Article in Eye (London, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed, 1 synthesis or guideline pooled it.
- MRI-based evaluation of cerebrospinal fluid dynamics and optic nerve subarachnoid space alterations in idiopathic intracranial hypertension and normal tension glaucoma: a systematic review.BMC medical imaging · 2026Pooled it
- Response to: 'Comment on: "Incidence of optic nerve kinking in a cohort of patients with Normal tension glaucoma"'.Eye (London, England) · 2025Article
- Comment on: "Incidence of optic nerve kinking in a cohort of patients with Normal tension glaucoma".Eye (London, England) · 2025Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo report on the incidence of optic nerve kinking in a series of patients diagnosed with normal-tension glaucoma (NTG) compared to an age- and gender matched control group without known optic nerve diseases. SUBJECTS AND
methodsAll patients with NTG who underwent imaging (computed tomography cysternography (CTC) or magnetic resonance imaging (MRI)) of the orbits and cranium between 2012 and 2022 were included, totalling 57 patients (27 females and 30 males; 57 eyes; mean age 69 ± 10 years). 57 age- and gender matched subjects without known optic nerve diseases who underwent MRI of the orbits and cranium served as controls. Radiographic images of the orbits were analysed for the presence of optic nerve kinking.
resultsIn the axial plane at least one optic nerve kink was found in 49 of 57 (86%) optic nerves in patients with NTG and in 10 of 57 (18%) optic nerves in controls (p < 0.0001) while in the sagittal plane in 28 of 57 (49%) optic nerves in patients with NTG and in 1 of 57 (2%) optic nerves in controls (p < 0.0001) (Fisher's two-tailed exact test).
conclusionsThis study demonstrates a high statistically significant incidence of optic nerve kinking in patients with NTG compared to controls without known optic nerve diseases. Its possible role involved in the pathophysiology of NTG needs to be evaluated.
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