Evidence map›Paper›PMID 39827227›Full record

ArticleDrug delivery and translational research2025

Robust peptide/RNA complexes prepared with microfluidic mixing for pulmonary delivery by nebulisation.

Cheng Ma, Michael Y T Chow, Chengyang Zhang, Paulina Goldbaum, Jamie Chien-Ming Hsieh, Jenny K W Lam

Abstract read
In one paragraph

Article in Drug delivery and translational research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Cheng MaUCL School of Pharmacy, University College London, 29-39 Brunswick Square, London, WC1N 1AX, UK.
Michael Y T ChowUCL School of Pharmacy, University College London, 29-39 Brunswick Square, London, WC1N 1AX, UK.
Chengyang ZhangUCL School of Pharmacy, University College London, 29-39 Brunswick Square, London, WC1N 1AX, UK.
Paulina GoldbaumUCL School of Pharmacy, University College London, 29-39 Brunswick Square, London, WC1N 1AX, UK.
Jamie Chien-Ming HsiehUCL School of Pharmacy, University College London, 29-39 Brunswick Square, London, WC1N 1AX, UK.
Jenny K W LamUCL School of Pharmacy, University College London, 29-39 Brunswick Square, London, WC1N 1AX, UK. jenny.lam@ucl.ac.uk.ORCID 0000-0003-2997-010X

Funding

Medical Research Council MRC IAA 2021 UCL MR/X502984/1University Research Committee, University of Hong Kong HKU Presidential PhD scholarship
6 · The paper itself

Abstract

Small interfering RNA (siRNA) and messenger RNA (mRNA) have drawn considerable attention in recent years due to their ability to modulate the expression of specific disease-related proteins. However, it is difficult to find safe, robust, and effective RNA delivery systems suitable for pulmonary delivery to treat lung diseases. In this study, two cationic peptides, namely LAH4-L1 and PEG

Indexed as

PeptidesRNA, MessengerRNA, Small InterferingA549 CellsAdministration, InhalationAerosolsCell LineHumansLungMicrofluidicsNebulizers and VaporizersParticle SizeTransfectionAerosolsPeptidesRNA, MessengerRNA, Small InterferingAerosolisationInhalationmRNAsiRNATransfectionVibrating mesh nebuliser

Identifiers

PMID39827227
PMCPMC12213855

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.