ArticleCell2025
Fine-tuning of gene expression through the Mettl3-Mettl14-Dnmt1 axis controls ESC differentiation.
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In one paragraph
Article in Cell, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
27 citing papers in PubMed.
- Sex-biased DNA methylation in small hive beetles (Aethina tumida).Insect molecular biology · 2026Article
- Regulation of PSAT1 and PHGDH by m6A in endocrine-resistant breast cancer cells.Biochimica et biophysica acta. Molecular basis of disease · 2026Article
- Epigenetic blind spots - the role of DNA methylation dynamics in stem cell-based models of embryogenesis.FEBS letters · 2026Article
- Emerging roles of mJournal of assisted reproduction and genetics · 2026Review
- Article
- Coordinated DNA 5-mC and RNA mExperimental & molecular medicine · 2026Article
- Bridging maternal effects and epitranscriptomics: A novel perspective in developmental biology.Developmental dynamics : an official publication of the American Association of Anatomists · 2026Review
- Pathological transcriptional retention of Cyp26b1 in perirenal adipose-derived stem cells contributes to MASLD progression.Hepatology international · 2026Article
- Succinate Prevents Mice Obesity by Enhancing Brown Adipocyte Thermogenesis via the SDH-METTL3-HIF1A Pathway.International journal of molecular sciences · 2026Article
- The Complex Role of Methylation in Regulating Vascular Smooth Muscle Cell Phenotypic States in Vascular Remodeling and Atherosclerosis.Biomolecules · 2026Review
- RNA modifications and epigenetic regulation in plants.aBIOTECH · 2026Review
- Regulatory elements on chromatin-associated RNA 15 years beyond RNA epigenetics.Nature chemical biology · 2026Review
- The expanding role of mAdvanced biotechnology · 2026Review
- Coordinated DNA methyltransferase 3A and methyltransferase-like 7A activity reprograms the tumor microenvironment through discoidin domain receptor 1 signaling.Cancer biology & medicine · 2026Article
- Targeting SPAK suppresses progression and averts an immune exhaustive microenvironment in hepatocellular carcinoma.Nature communications · 2026Article
- M6AREG 2.0: the landscape of m6A-centered crosstalk with diverse epigenetic regulation.Nucleic acids research · 2026Article
- Multi-Omics Analysis Reveals m7G Methylation-Related Genes May Be Involved in TGF-β Signaling-Mediated Anti-PD-L1 Response in Bladder Cancer.ImmunoTargets and therapy · 2026Article
- The crosstalk of m6A modification and non-coding RNAs in gastric cancer: biomarkers and therapeutic potentials.Cancer cell international · 2025Review
- METTL3 safeguards cell identity and epigenome of human trophoblast stem cells.Nature communications · 2025Article
- Immunoregulatory roles of post-translational modifications in colorectal cancer: mechanisms and therapeutic implications.Cellular and molecular life sciences : CMLS · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
41 authors.
Giuseppe QuartoLaboratory of Cancer Epigenetics, Faculty of Medicine, ULB-Cancer Research Center (U-CRC), Université libre de Bruxelles (ULB), Institut Jules Bordet, Brussels, Belgium.
Andrea Li GreciLaboratory of Cancer Epigenetics, Faculty of Medicine, ULB-Cancer Research Center (U-CRC), Université libre de Bruxelles (ULB), Institut Jules Bordet, Brussels, Belgium.
Martin BizetLaboratory of Cancer Epigenetics, Faculty of Medicine, ULB-Cancer Research Center (U-CRC), Université libre de Bruxelles (ULB), Institut Jules Bordet, Brussels, Belgium.
Audrey PenningLaboratory of Cancer Epigenetics, Faculty of Medicine, ULB-Cancer Research Center (U-CRC), Université libre de Bruxelles (ULB), Institut Jules Bordet, Brussels, Belgium.
Irina PrimacLaboratory of Cancer Epigenetics, Faculty of Medicine, ULB-Cancer Research Center (U-CRC), Université libre de Bruxelles (ULB), Institut Jules Bordet, Brussels, Belgium.
Frédéric MurisierLaboratory of Cancer Epigenetics, Faculty of Medicine, ULB-Cancer Research Center (U-CRC), Université libre de Bruxelles (ULB), Institut Jules Bordet, Brussels, Belgium.
Liliana Garcia-MartinezSylvester Comprehensive Cancer Center, Department of Human Genetics, University of Miami Miller School of Medicine, Miami, FL, USA.
Rodrigo L BorgesSylvester Comprehensive Cancer Center, Department of Human Genetics, University of Miami Miller School of Medicine, Miami, FL, USA.
Qingzeng GaoChemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Department of Pharmacology, Weill Cornell Medicine, New York, NY, USA.
Pradeep K R CingaramSylvester Comprehensive Cancer Center, Department of Human Genetics, University of Miami Miller School of Medicine, Miami, FL, USA.
Emilie CalonneLaboratory of Cancer Epigenetics, Faculty of Medicine, ULB-Cancer Research Center (U-CRC), Université libre de Bruxelles (ULB), Institut Jules Bordet, Brussels, Belgium.
Bouchra HassabiLaboratory of Cancer Epigenetics, Faculty of Medicine, ULB-Cancer Research Center (U-CRC), Université libre de Bruxelles (ULB), Institut Jules Bordet, Brussels, Belgium.
Céline HubertLaboratory of Cancer Epigenetics, Faculty of Medicine, ULB-Cancer Research Center (U-CRC), Université libre de Bruxelles (ULB), Institut Jules Bordet, Brussels, Belgium.
Adèle HerpoelLaboratory of Cancer Epigenetics, Faculty of Medicine, ULB-Cancer Research Center (U-CRC), Université libre de Bruxelles (ULB), Institut Jules Bordet, Brussels, Belgium.
Pascale PutmansLaboratory of Cancer Epigenetics, Faculty of Medicine, ULB-Cancer Research Center (U-CRC), Université libre de Bruxelles (ULB), Institut Jules Bordet, Brussels, Belgium.
Frédérique MiesLaboratory of Cancer Epigenetics, Faculty of Medicine, ULB-Cancer Research Center (U-CRC), Université libre de Bruxelles (ULB), Institut Jules Bordet, Brussels, Belgium.
Jérôme MartinLaboratory of Cancer Epigenetics, Faculty of Medicine, ULB-Cancer Research Center (U-CRC), Université libre de Bruxelles (ULB), Institut Jules Bordet, Brussels, Belgium.
Louis Van der LindenLaboratory of Cancer Epigenetics, Faculty of Medicine, ULB-Cancer Research Center (U-CRC), Université libre de Bruxelles (ULB), Institut Jules Bordet, Brussels, Belgium.
Gaurav DubeLaboratory of Cancer Epigenetics, Faculty of Medicine, ULB-Cancer Research Center (U-CRC), Université libre de Bruxelles (ULB), Institut Jules Bordet, Brussels, Belgium.
Pankaj KumarLaboratory of Cancer Epigenetics, Faculty of Medicine, ULB-Cancer Research Center (U-CRC), Université libre de Bruxelles (ULB), Institut Jules Bordet, Brussels, Belgium.
Romuald SoinLaboratory of Molecular Biology of the Gene, Department of Molecular Biology, Université libre de Bruxelles (ULB), Gosselies, Belgium.
Abhay KumarGreehey Children's Cancer Research Institute and Department of Biochemistry and Structural Biology, University of Texas Health Science Center, San Antonio, TX, USA.
Anurag MisraGreehey Children's Cancer Research Institute and Department of Biochemistry and Structural Biology, University of Texas Health Science Center, San Antonio, TX, USA.
Jie LanLaboratory of Cancer Epigenetics, Faculty of Medicine, ULB-Cancer Research Center (U-CRC), Université libre de Bruxelles (ULB), Institut Jules Bordet, Brussels, Belgium.
Morgane PaqueLaboratory of Cancer Signaling, GIGA-Institute, University of Liège, Liège, Belgium; WELBIO Department, WEL Research Institute, Wavre, Belgium.
Yogesh K GuptaGreehey Children's Cancer Research Institute and Department of Biochemistry and Structural Biology, University of Texas Health Science Center, San Antonio, TX, USA.
Arnaud BlommeLaboratory of Cancer Signaling, GIGA-Institute, University of Liège, Liège, Belgium; WELBIO Department, WEL Research Institute, Wavre, Belgium.
Pierre CloseLaboratory of Cancer Signaling, GIGA-Institute, University of Liège, Liège, Belgium; WELBIO Department, WEL Research Institute, Wavre, Belgium.
Pierre-Olivier EstèveNew England Biolabs, Inc., Ipswich, MA, USA.
Elizabeth A CainePromega Corporation, Madison, WI, USA.
Kristin M RichingPromega Corporation, Madison, WI, USA.
Cyril GueydanLaboratory of Molecular Biology of the Gene, Department of Molecular Biology, Université libre de Bruxelles (ULB), Gosselies, Belgium.
Danette L DanielsFoghorn Therapeutics, Cambridge, MA, USA.
Sriharsa PradhanNew England Biolabs, Inc., Ipswich, MA, USA.
Ramin ShiekhattarSylvester Comprehensive Cancer Center, Department of Human Genetics, University of Miami Miller School of Medicine, Miami, FL, USA.
Yael DavidChemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Department of Pharmacology, Weill Cornell Medicine, New York, NY, USA.
Lluis MoreySylvester Comprehensive Cancer Center, Department of Human Genetics, University of Miami Miller School of Medicine, Miami, FL, USA.
Jana JeschkeLaboratory of Cancer Epigenetics, Faculty of Medicine, ULB-Cancer Research Center (U-CRC), Université libre de Bruxelles (ULB), Institut Jules Bordet, Brussels, Belgium.
Rachel DeplusLaboratory of Cancer Epigenetics, Faculty of Medicine, ULB-Cancer Research Center (U-CRC), Université libre de Bruxelles (ULB), Institut Jules Bordet, Brussels, Belgium.
Evelyne CollignonLaboratory of Cancer Epigenetics, Faculty of Medicine, ULB-Cancer Research Center (U-CRC), Université libre de Bruxelles (ULB), Institut Jules Bordet, Brussels, Belgium.
François FuksLaboratory of Cancer Epigenetics, Faculty of Medicine, ULB-Cancer Research Center (U-CRC), Université libre de Bruxelles (ULB), Institut Jules Bordet, Brussels, Belgium. Electronic address: francois.fuks@ulb.be.
Funding
X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4MTumor Biology Research ProgramP30CA240139 · NCI · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI George S. Grills · 2019 to 2026
$24.1MElucidation of Integrator's FunctionR01GM078455 · NIGMS · WISTAR INSTITUTE · PI SHIEKHATTAR, RAMIN · 2010 to 2025
$5.1MMechanism-based Targeting of the RNA Processing Machinery of SARS-CoV-2R01AI161363 · NIAID · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI GUPTA, YOGESH K · 2021 to 2025
$3.2MAltering the chromostasis and genome stability by modulating histone methylationR01GM146409 · NIGMS · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI MOREY, LLUIS, VERDUN, RAMIRO ERNESTO · 2022 to 2025
$1.7MMechanisms of RING1B and PRC1 complexes in transcriptional activationR01GM141349 · NIGMS · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI Lluis Morey · 2022 to 2026
$1.6MNCI NIH HHS P30 CA008748NCI NIH HHS P30 CA240139NIAID NIH HHS R01 AI161363NIGMS NIH HHS R01 GM078455NIGMS NIH HHS R01 GM141349NIGMS NIH HHS R01 GM146409
Abstract
The marking of DNA, histones, and RNA is central to gene expression regulation in development and disease. Recent evidence links N6-methyladenosine (m
Indexed as
Cell DifferentiationDNA (Cytosine-5-)-Methyltransferase 1Embryonic Stem CellsMethyltransferasesAdenosineAnimalsChromatinDNA MethylationEmbryoid BodiesEpigenesis, GeneticHumansMiceMouse Embryonic Stem CellsAdenosineChromatinDNA (Cytosine-5-)-Methyltransferase 1Dnmt1 protein, mouseMethyltransferasesMettl14 protein, mouseMettl3 protein, mouseN-methyladenosinedifferentiationDNA methylationDNMT1epigeneticsepitranscriptomicsESCsgene expressionm(6)AMETTL14METTL3
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.