Evidence map›Paper›PMID 39825944›Full record

ArticleArchives of dermatological research2025

Comparison of health-related quality of life in atopic dermatitis, hidradenitis suppurativa, pemphigus and psoriasis.

Péter György Balázs, Krisztián Gáspár, Hunor L Gergely, Krisztina Hajdú, Péter Holló, Kamilla Koszorú, Adrienn Katalin Poór, Miklós Sárdy, Andrea Szegedi, Béla Tamási and 2 more

Abstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Archives of dermatological research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Péter György BalázsInstitute of Social and Political Sciences, Corvinus University of Budapest, Budapest, Hungary. peter.balazs@uni-corvinus.hu.ORCID http://orcid.org/0000-0002-1760-2601
Krisztián GáspárFaculty of Medicine, University of Debrecen, Debrecen, Hungary.
Hunor L GergelyFaculty of Medicine, Semmelweis University, Budapest, Hungary.
Krisztina HajdúFaculty of Medicine, University of Debrecen, Debrecen, Hungary.
Péter HollóFaculty of Medicine, Semmelweis University, Budapest, Hungary.
Kamilla KoszorúFaculty of Medicine, Semmelweis University, Budapest, Hungary.
Adrienn Katalin PoórFaculty of Medicine, Semmelweis University, Budapest, Hungary.
Miklós SárdyFaculty of Medicine, Semmelweis University, Budapest, Hungary.
Andrea SzegediFaculty of Medicine, University of Debrecen, Debrecen, Hungary.
Béla TamásiFaculty of Medicine, Semmelweis University, Budapest, Hungary.
Norbert WikonkálFaculty of Medicine, Semmelweis University, Budapest, Hungary.
Valentin BrodszkyInstitute of Social and Political Sciences, Corvinus University of Budapest, Budapest, Hungary.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aims to explore the measurement agreement between direct and indirect health utility measures in four chronic dermatological conditions (atopic dermatitis, hidradenitis suppurativa, pemphigus, psoriasis). Outpatients survey data collected between 2015 and 2021 were analysed. Health-related quality of life (HRQoL) outcome measures included time trade-off (TTO), EQ-5D-5L and Dermatology Life Quality Index (DLQI). Descriptive statistics were computed for the pooled sample and four diseases. Mean, standard deviation (SD), median, interquartile range (IQR), ceiling and floor effects were calculated for TTO, EQ-5D-5L and DLQI utilities. Bland‒Altman plots and intraclass correlation coefficients (ICC) were applied to investigate the agreement between health utility measures. Sociodemographic characteristics (age, sex, educational level, employment status) and health-related information (disease duration, outpatient care visits in the past 3 months and disease severity) impact on utilities was investigated by Tobit regressions. The sample includes N = 765 patient responses with a mean age of 41.5 (SD = 16.2), majority being males (52.7%). Total sample mean utilities were the highest according to TTO (0.83), followed by EQ-5D-5L and vDLQI (0.81 and 0.81) and lowest in mDLQI (0.77). Measurement agreement was found only between TTO and EQ-5D-5L. Skin-disease severity impacted all health state utilities, though only TTO differentiated utility values according to disease type. The discrepancies between the TTO and DLQI warn to compare DLQI-based utilities in different dermatological conditions with extreme caution.

Indexed as

Dermatitis, AtopicHidradenitis SuppurativaPemphigusPsoriasisQuality of LifeAdultFemaleHumansMaleMiddle AgedSeverity of Illness IndexSurveys and QuestionnairesYoung AdultAtopic dermatitisHealth utility measurement agreementHidradenitis suppurativaHRQoL outcome measurePemphigusPsoriasis

Identifiers

PMID39825944
PMCPMC11742771

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.