Evidence map›Paper›PMID 39825711›Full record

ArticleJournal of anatomy2025

Obesity and hypoxia have differential effects on myocardial innervation in the right ventricle of the male mouse heart.

Louisa-Chiara Mierswa, Julia Schipke, Christian Mühlfeld

Abstract read
In one paragraph

Article in Journal of anatomy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Louisa-Chiara MierswaHannover Medical School, Institute of Functional and Applied Anatomy, Hannover, Germany.
Julia SchipkeHannover Medical School, Institute of Functional and Applied Anatomy, Hannover, Germany.
Christian MühlfeldHannover Medical School, Institute of Functional and Applied Anatomy, Hannover, Germany.ORCID 0000-0002-7827-4867

Funding

Deutsches Zentrum für LungenforschungElse Kröner-Fresenius-Stiftung 2019_A22
6 · The paper itself

Abstract

Obesity, along with hypoxia, is known to be a risk factor for pulmonary hypertension (PH), which can lead to right ventricular hypertrophy and eventually heart failure. Both obesity and PH influence the autonomic nervous system (ANS), potentially aggravating changes in the right ventricle (RV). This study investigates the combined effects of obesity and hypoxia on the autonomic innervation of the RV in a mouse model. Male C57BL/6N mice were subjected to a control diet (CD) or a high-fat diet (HFD) for 30 weeks, with subsets of the mice exposed to chronic normobaric hypoxia (13% O

Indexed as

Heart VentriclesHypoxiaObesityAnimalsDiet, High-FatMaleMiceMice, Inbred C57BLMyocardiumautonomic nervous systemchronic hypoxiaobesityright ventricle

Identifiers

PMID39825711
PMCPMC12159321

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.