Evidence map›Paper›PMID 39825651›Full record

ArticleZhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics2025

[Clinical sub-phenotypes of acute kidney injury in children and their association with prognosis].

Lian Feng, Min Li, Zhen Jiang, Jiao Chen, Zhen-Jiang Bai, Xiao-Zhong Li, Guo-Ping Lu, Yan-Hong Li

Abstract readEnglish Abstract
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Article in Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Lian FengDepartment of Nephrology and Immunology, Children's Hospital of Soochow University, Suzhou, Jiangsu 215000, China.
Min Li
Zhen Jiang
Jiao Chen
Zhen-Jiang Bai
Xiao-Zhong LiDepartment of Nephrology and Immunology, Children's Hospital of Soochow University, Suzhou, Jiangsu 215000, China.
Guo-Ping Lu
Yan-Hong LiDepartment of Nephrology and Immunology, Children's Hospital of Soochow University, Suzhou, Jiangsu 215000, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo investigate the clinical sub-phenotype (SP) of pediatric acute kidney injury (AKI) and their association with clinical outcomes.

methodsGeneral status and initial values of laboratory markers within 24 hours after admission to the pediatric intensive care unit (PICU) were recorded for children with AKI in the derivation cohort (

resultsIn the derivation cohort, two clinical SPs of AKI (SP1 and SP2) were identified by the two-step cluster analysis using the 20 variables screened by LASSO regression, namely SP

conclusionsThis study establishes a parsimonious classifier model and identifies two clinical SPs of AKI with different clinical features and outcomes.The SP2 group has more severe disease and worse clinical prognosis.

Indexed as

Acute Kidney InjuryAdolescentChildChild, PreschoolFemaleHumansInfantLogistic ModelsMalePhenotypePrognosisAcute kidney injuryChildClinical sub-phenotypeMultiple organ dysfunction syndromePrognosis

Identifiers

PMID39825651
PMCPMC11750252

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