ArticleMagnetic resonance in medicine2025
Quantifying spatial and dynamic lung abnormalities with 3D PREFUL FLORET UTE imaging: A feasibility study.
Article in Magnetic resonance in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- RadiolGAN: Multicenter Feasibility Study of Synthetic CT From 3D Ultra-Short Echo Time MRI for Enhanced Pulmonary Radiologic Sign Visualization.Journal of magnetic resonance imaging : JMRI · 2026Article
- Phase-Pole-Free Images and Smooth Coil Sensitivity Maps by Regularized Nonlinear Inversion.Magnetic resonance in medicine · 2026Article
- Comparison of Signal- and Volume-Based Ventilation-Weighted Assessment Using 3D FLORET UTE MRI in Patients With Various Pulmonary Disease.Magnetic resonance in medicine · 2026Article
- Self-Supervised Joint Reconstruction and Denoising of T2-Weighted PROPELLER MRI of the Lung at 0.55T.Magnetic resonance in medicine · 2026Article
- Coil Sketching for Fast and Efficient 4D Lung MRI Reconstruction.Magnetic resonance in medicine · 2026Article
- Comparison of phase-resolved functional lung (PREFUL) and hyperpolarizedPediatric radiology · 2025Article
- Magnetic Resonance Imaging in the Clinical Evaluation of Lung Disorders: Current Status and Future Prospects.Journal of magnetic resonance imaging : JMRI · 2025Review
- Functional Pulmonary Imaging.Journal of magnetic resonance imaging : JMRI · 2025Review
- Optimizing Xenon 129 Ventilation MRI in Cystic Fibrosis with Spiral Imaging and Flip-Angle Correction.Radiology. Cardiothoracic imaging · 2025Article
- Dual-Center Repeatability, Consistency, and Comparison of 3D Phase-Resolved Functional (PREFUL) Ventilation MRI at 3 and 1.5 T in Healthy Volunteers.NMR in biomedicine · 2025Article
- Quantifying spatial and dynamic lung abnormalities with 3D PREFUL FLORET UTE imaging: A feasibility study.Magnetic resonance in medicine · 2025Article
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Authors and funding
13 authors.
Funding
Abstract
purposePulmonary MRI faces challenges due to low proton density, rapid transverse magnetization decay, and cardiac and respiratory motion. The fermat-looped orthogonally encoded trajectories (FLORET) sequence addresses these issues with high sampling efficiency, strong signal, and motion robustness, but has not yet been applied to phase-resolved functional lung (PREFUL) MRI-a contrast-free method for assessing pulmonary ventilation during free breathing. This study aims to develop a reconstruction pipeline for FLORET UTE, enhancing spatial resolution for three-dimensional (3D) PREFUL ventilation analysis.
methodsThe FLORET sequence was used to continuously acquire data over 7 ± 2 min in 36 participants, including healthy subjects (N = 7) and patients with various pulmonary conditions (N = 29). Data were reconstructed into respiratory images using motion-compensated low-rank reconstruction, and a 3D PREFUL algorithm was adapted to quantify static and dynamic ventilation surrogates. Image sharpness and signal-to-noise ratio were evaluated across different motion states. PREFUL ventilation metrics were compared with static
resultsOptimal image sharpness and accurate ventilation dynamics were achieved using 24 respiratory bins, leading to their use in the study. A strong correlation was found between 3D PREFUL FLORET UTE ventilation defect percentages (VDPs) and
conclusionThe proposed reconstruction pipeline for FLORET UTE MRI offers improved spatial resolution and strong correlation with
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