Evidence map›Paper›PMID 39825441›Full record

ArticleTrials2025

Efficacy and safety of perioperative analgesia in PENG block for children undergoing hip surgery with developmental dysplasia: study protocol for a randomized, double-blinded, non-inferiority trial.

Mingzhe Xu, Yi He, Zhi Li, Bin Du

Abstract readClinical Trial Protocol
In one paragraph

Article in Trials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Mingzhe XuDepartment of Anesthesiology, West China Hospital, Sichuan University, Chengdu, China.
Yi HeDepartment of Anesthesiology, West China Hospital, Sichuan University, Chengdu, China.
Zhi LiDepartment of Critical Care Medicine, Cheng Du Shang Jin Nan Fu Hospital, West China Hospital of Sichuan University, Chengdu, China.
Bin DuDepartment of Anesthesiology, West China Hospital, Sichuan University, Chengdu, China. phoenixdb2008@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSurgical intervention is critical in the treatment of hip developmental dysplasia in children. Perioperative analgesia, usually based on high opioid dosages, is frequently used in these patients. In some circumstances, regional anesthetic procedures such as caudal block and lumbar plexus block have also been used. Previous research has shown that pericapsular nerve group (PENG) block provides excellent anesthetic efficacy during open hip surgery in adults. PENG block is thought to provide a similar analgesia effect comparable to caudal block.

methodsThis study is a single-center, prospective, randomized, double-blinded, non-inferiority experiment that enrolled children aged 6 months to 7 years who were scheduled for developmental dysplasia hip surgery. Following general anesthesia and regional blocks (0.25% ropivacaine at a dose of 2.5 mg·kg DISCUSSION: We expect this trial to provide some evidences that PENG block is safe and effective for perioperative analgesia in pediatric patients undergoing open hip surgery.

trial registrationChinese Clinical Trial Registry ChiCTR2100053128. Registered on November 12, 2021.

Indexed as

AnalgesiaDevelopmental Dysplasia of the HipNerve BlockPostoperative PainAnalgesics, OpioidAnesthetics, LocalChildChild, PreschoolDouble-Blind MethodEquivalence Trials as TopicFemaleHumansInfantMalePain MeasurementProspective StudiesAnalgesics, OpioidAnesthetics, LocalRopivacaineChildrenDevelopmental dysplasiaHip surgeryPericapsular nerve group blockPerioperative analgesiaRandomized trial

Identifiers

PMID39825441
PMCPMC11742540

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.