Evidence map›Paper›PMID 39825328›Full record

ArticleBMC nursing2025

Relationship of negative life events with depression and anxiety in nursing students: a moderated mediation model of resilience and gender.

Xiaoli Ye, Guihong Yang, Wei Zhang, Loren Toussaint, Fangfang Zhao

Abstract read
In one paragraph

Article in BMC nursing, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Xiaoli Ye *School of Nursing and Rehabilitation, Nantong University, Qixiu Road 19#, Nantong, 226001, Jiangsu, PR China.
Guihong Yang *School of Nursing and Rehabilitation, Nantong University, Qixiu Road 19#, Nantong, 226001, Jiangsu, PR China.
Wei ZhangSchool of Nursing and Rehabilitation, Nantong University, Qixiu Road 19#, Nantong, 226001, Jiangsu, PR China.
Loren ToussaintDepartment of Psychology, Luther College, Decorah, IA, USA.
Fangfang ZhaoSchool of Nursing and Rehabilitation, Nantong University, Qixiu Road 19#, Nantong, 226001, Jiangsu, PR China. moonstar148@hotmail.com.

Funding

Humanities and Social Science Fund of Ministry of Education of China 19YJCZH261National Social Science Fund of China 21BSH007Philosophy and Social Science Research in Colleges and Universities in Jiangsu Province 2024SJYB1242Postgraduate Research &Practice innovation Program of Jiangsu Province KYCX24_3600/SJCX24_2030
6 · The paper itself

Abstract

backgroundCompared to ordinary student in the same age group, nursing students experience notably higher rates of depression and anxiety. Negative life events (NLEs) and resilience were recognized as risk factors and protective factors, respectively. There is little literature on the complex interaction of these factors among nursing students.

objectivesThe study aims to explore the potential relationship of NLEs, resilience, and gender with symptoms of depression and anxiety among nursing students.

methodsA cross-sectional design was used for this study. A total of 568 participants from three universities in East, South and North China were recruited. Data collection instruments included socio-demographic characteristics, the Patient Health Questionnaire-9, the Generalized Anxiety Disorder Scale, the 10-item Connor-Davidson Resilience Scale, the Adolescent Life Events Self-Rating Scale, and The Pittsburgh Sleep Quality Index. A moderated mediation model was used to analyze the data.

resultsNLEs and resilience significantly related to depression and anxiety (r = -0.289 ~ 0.454, all ps < 0.01). NLEs had a direct effect on depression (B = 0.251, p < 0.001) and anxiety (B = 0.307, p < 0.001). Analysis of mediating effects revealed that NLEs influenced depression (B = 0.02, 95% CI : 0.004-0.041) and anxiety (B = 0.019, 95% CI : 0.004-0.040) through resilience pathways. Additionally, gender was found to have a moderating effect on the direct association of NLEs with anxiety (B = -0.031, p < 0.05), with males showing a greater association.

conclusionsThe findings suggest that improving resilience may help break the relationship of NLEs with depression and anxiety in nursing students. Additionally, the mental health of male nursing students needs more attention.

Indexed as

AnxietyDepressionNegative life eventsNursing studentsResilience

Identifiers

PMID39825328
PMCPMC11740486

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LicenceCC BY-NC-ND
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.