Evidence map›Paper›PMID 39825304›Full record

ArticleBMC ophthalmology2025

Herpes zoster ophthalmicus with acute retrobulbar optic neuritis and abducens nerve palsy: a case report.

Farshad Afshar, Mohammad Sadegh Khalilian, Mohsen Pourazizi, Mohammad Amin Najafi

Abstract readCase Reports
In one paragraph

Article in BMC ophthalmology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Farshad AfsharIsfahan Eye Research Center, Department of Ophthalmology, Isfahan University of Medical Sciences, Isfahan, Iran.
Mohammad Sadegh KhalilianIsfahan Eye Research Center, Department of Ophthalmology, Isfahan University of Medical Sciences, Isfahan, Iran. m.khalilian74@gmail.com.
Mohsen PouraziziIsfahan Eye Research Center, Department of Ophthalmology, Isfahan University of Medical Sciences, Isfahan, Iran.
Mohammad Amin NajafiIsfahan Neurosciences Research Center, Alzahra Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Herpes zoster Ophthalmicus (HZO) affecting the ophthalmic division (V1) of the trigeminal nerve. HZO may cause extraocular muscle palsies, with the third nerve being the most commonly affected and the fourth nerve the least. The combined involvement of the optic nerve and isolated paralysis of the eye muscle is very rare, with only limited case reports documenting this complication of ocular herpes zoster. This case report also describes a case of optic nerve involvement with 6th nerve palsy, which was treated with corticosteroid and valacyclovir.

Indexed as

Abducens Nerve DiseasesEye Infections, ViralHerpes Zoster OphthalmicusOptic NeuritisAcute DiseaseAcyclovirAntiviral AgentsFemaleGlucocorticoidsHumansMagnetic Resonance ImagingMaleValacyclovirAcyclovirAntiviral AgentsGlucocorticoidsValacyclovirAbducens nerve palsyAcute retrobulbar optic neuritis (ON)Herpes zosterHerpes zoster Ophthalmicus (HZO)OphthalmoplegiaSixth cranial nerve palsy

Identifiers

PMID39825304
PMCPMC11740321

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.