ArticleBMC nursing2025
Fear of progression and quality of life in patients with heart failure: a cross-sectional study on the multiple mediation of psychological distress and resilience.
Article in BMC nursing, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Article
- Factors associated with depression among tuberculosis patients with HIV co-infection in rural community Thailand.BMC psychology · 2026Article
- The development and validation of a clinical measurement tool for fear of recurrence and progression in cardiac patients.Scientific reports · 2026Article
- Role of psychological resilience and psychological distress in linking fear of disease progression to quality of life in chronic heart failure: a cross-sectional serial mediation analysis.Frontiers in psychiatry · 2026Article
- Self-Disclosure and Fear of Progression in Younger and Middle-Aged Adults with Diabetes: Chain-Mediating Roles of Social Support and Illness Perception.Patient preference and adherence · 2026Article
- The association between fear of disease progression and financial toxicity in patients with chronic osteomyelitis: a cross-sectional study.Frontiers in psychology · 2026Article
- Prevalence and associated factors of fear of progression in patients with heart failure in China: a scoping review.Frontiers in psychiatry · 2026Review
- The mediating role of rumination between fear of disease progression and sleep disturbance in melanoma patients: a dual-perspective analysis based on person-centered and variable-centered approaches.Frontiers in public health · 2025Article
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Authors and funding
6 authors.
Funding
Abstract
backgroundExisting research indicates that fear of progression influences the quality of life of patients with various diseases. However, the influence of fear of progression on the quality of life of patients with heart failure and its underlying mechanisms remain unclear. This study aimed to identify the link between fear of progression and quality of life in patients with heart failure and explore the multiple mediating roles of psychological distress and resilience in this association.
methodsThis multicenter, cross-sectional study was conducted between March and December 2023 across four tertiary hospitals in China. Data on fear of progression, psychological distress (anxiety and depression), resilience, and quality of life were collected. The PROCESS macro in SPSS was used to analyze the multiple mediation model.
resultsThe study involved 277 patients. The total indirect effect of fear of progression on quality of life was significant. Fear of progression influenced physical quality of life through two pathways: (i) resilience independently, and (ii) psychological distress-depression and resilience serially. Additionally, fear of progression influenced mental quality of life through three pathways: (i) psychological distress (anxiety and depression) independently, (ii) resilience independently, and (iii) psychological distress (anxiety and depression) and resilience serially. However, psychological distress-anxiety or resilience had no mediating effect on the relationship between fear of progression and physical quality of life in patients with heart failure.
conclusionsFear of progression had a negative association with quality of life in patients with heart failure. In addition, the relationship between fear of progression and quality of life was mediated by psychological distress and resilience. Interventions targeting the reduction of psychological distress and enhancement of resilience may mitigate the impact of fear of progression on quality of life in patients with heart failure.
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