Evidence map›Paper›PMID 39825251›Full record

SynthesisBMC pregnancy and childbirth2025

Panic disorder during pregnancy and the first three years after delivery: a systematic review.

F Gerrik Verhees, Antonia Bendau, Stefanie Unger, Katharina L Donix, Eva Asselmann, Julia Martini

Abstract readSystematic Review
In one paragraph

Synthesis in BMC pregnancy and childbirth, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

F Gerrik VerheesDepartment of Psychiatry & Psychotherapy, Faculty of Medicine, Carl Gustav Carus University Hospital, Technische Universität Dresden, Dresden, Germany.ORCID http://orcid.org/0000-0002-6808-2968
Antonia BendauFaculty of Health, HMU Health and Medical University, Potsdam, Germany.ORCID http://orcid.org/0000-0002-3789-6205
Stefanie UngerDepartment of Psychiatry & Psychotherapy, Faculty of Medicine, Carl Gustav Carus University Hospital, Technische Universität Dresden, Dresden, Germany.ORCID http://orcid.org/0000-0003-2775-1456
Katharina L DonixDepartment of Psychiatry & Psychotherapy, Faculty of Medicine, Carl Gustav Carus University Hospital, Technische Universität Dresden, Dresden, Germany.ORCID http://orcid.org/0009-0006-3625-0126
Eva Asselmann *Faculty of Health, HMU Health and Medical University, Potsdam, Germany.ORCID http://orcid.org/0000-0002-2132-8852
Julia Martini *Department of Psychiatry & Psychotherapy, Faculty of Medicine, Carl Gustav Carus University Hospital, Technische Universität Dresden, Dresden, Germany. Julia.Martini@tu-dresden.de.ORCID http://orcid.org/0000-0002-9524-8257

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPanic disorder (PD) is highly prevalent during the peripartum period. The aim of this systematic review was to summarize evidence on risk factors and course patterns of peripartum PD as well as maternal, infant or dyadic outcomes during the first three years after delivery.

methodsA literature search was conducted according to PRISMA guidelines. Inclusion criteria were: (1) a diagnosis of PD or panic attacks during pregnancy, (2) risk factors and course as well as maternal, infant or dyadic outcomes measured in pregnancy and/or up to 3 years postpartum (3) peer-reviewed articles in English or German published between 1980 and April 2024. After screening of n = 2,740 records, n = 75 records based on n = 64 projects were eligible for this systematic review.

resultsOverall, n = 47 studies investigated the course of PD during the peripartum period, n = 23 studies examined the associations of PD and obstetric, neonatal or infant outcomes, and n = 5 studies focused on the associations of PD and characteristics of the mother-infant dyad. We found (1) no common trajectory, but heterogeneous courses of maternal PD in the peripartum period, (2) associations of maternal PD with birth complications and subsequent postpartum depression, and (3) evidence for associations of PD with infant and dyadic outcomes. LIMITATIONS: Diverse outcome measures in recent original publications did not allow for a meta-analytic approach.

conclusionHeterogenous courses and outcomes of peripartum PD require comprehensive monitoring of affected mothers and their infants. There is a need for further longitudinal investigations into familial transmission of anxiety disorders.

Indexed as

Panic DisorderPregnancy ComplicationsDepression, PostpartumFemaleHumansInfant, NewbornPeripartum PeriodPostpartum PeriodPregnancyRisk FactorsAnxiety/panic disorderDyadicMaternal healthPanicPeripartumPostpartumPregnancy

Identifiers

PMID39825251
PMCPMC11740555

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.