SynthesisBMC anesthesiology2025
Outcome and complications in postcardiotomy cardiogenic shock treated with extracorporeal life support - a systematic review and meta-analysis.
Synthesis in BMC anesthesiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Inflammatory Cytokines as Early Predictors of Weaning Failure From Extracorporeal Life Support.Artificial organs · 2026Article
- Outcomes of patients receiving extracorporeal membrane oxygenation: DirectWorld journal of transplantation · 2025Article
- Circulatory Support for High-Risk Coronary Artery Bypass Grafting and Coronary Interventions: Where is the Evidence?The International journal of angiology : official publication of the International College of Angiology, Inc · 2025Review
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Authors and funding
18 authors.
Funding
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Abstract
backgroundPostcardiotomy cardiogenic shock (PCCS) in cardiac surgery is associated with a high rate of morbidity and mortality. Beside other therapeutic measures (e.g. intraaortic balloon pump (IABP)), extracorporeal life support is being increasingly used in this particular form of shock. Objectives of this meta-analysis were to determine mortality and complications of extracorporeal life support treatment (ECLS) in cardiac surgery patients, and if outcomes were influenced by a preexisting cardiovascular risk profile.
methodsMEDLINE and EMBASE were searched for studies in English, published between January 1
resultsTwo thousand, seven hundred seventy-four papers were screened, of which 132 full text articles were assessed for suitability. 70 remaining studies were included for further evaluation and data analysis. Five studies could be included in the final analysis since the corresponding authors provided additional necessary information. Successful weaning from extracorporeal life support was accomplished in 52.8% (30.8%-57.4%) and 31.1% were discharged alive (mortality of 25.0 - 56.2% after weaning). 95.1% of all treated patients suffered from at least one complication. Diabetes mellitus and obesity seem to be independent risk factors for poor outcome.
conclusionsExtracorporeal life support for PCCS is associated with a substantial mortality and complication rate. Diabetes mellitus and obesity seem to be independent risk factors. Therefore, until future work has elucidated which patients benefit at all, the risks of ECLS-treatment must be critically weighed up against a possible benefit.
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