Evidence map›Paper›PMID 39825247›Full record

ArticleBMC medical imaging2025

Ultrasonographic examination of the maturational effect of maternal vitamin D use on fetal clavicle bone development.

Fatma Ozdemir, Banu Acmaz, Fatma Latifoglu, Sabahattin Muhtaroglu, Nefise Tanrıdan Okcu, Gokhan Acmaz, Iptisam Ipek Muderris

Abstract read
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In one paragraph

Article in BMC medical imaging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Fatma OzdemirFaculty of Medicine, Department of Obstetrics and Gynecology, Erciyes University, Yenidogan Neighborhood, Turhan Baytop Street No:1, Kayseri, 38280, Turkey. dr.ftmozdemir@gmail.com.
Banu AcmazDepartment of Internal Medicine, Kayseri City Hospital, Kayseri, Turkey.
Fatma LatifogluFaculty of Engineering, Department of Biomedical Engineering, Erciyes University, Kayseri, Turkey.
Sabahattin MuhtarogluFaculty of Medicine, Department of Biochemistry, Erciyes University, Kayseri, Turkey.
Nefise Tanrıdan OkcuDepartment of Obstetrics and Gynecology, Adana City Hospital, Adana, Turkey.
Gokhan AcmazFaculty of Medicine, Department of Obstetrics and Gynecology, Erciyes University, Yenidogan Neighborhood, Turhan Baytop Street No:1, Kayseri, 38280, Turkey.
Iptisam Ipek MuderrisFaculty of Medicine, Department of Obstetrics and Gynecology, Erciyes University, Yenidogan Neighborhood, Turhan Baytop Street No:1, Kayseri, 38280, Turkey.

Funding

Erciyes University Scientific Research Projects Unit TSA-2020-10207
6 · The paper itself

Abstract

aimThis study aimed to evaluate the effect of maternal vitamin D use during intrauterine life on fetal bone development using ultrasonographic image processing techniques. MATERIALS AND

methodsWe evaluated 52 pregnant women receiving vitamin D supplementation and 50 who refused vitamin D supplementation. Ultrasonographic imaging was performed on the fetal clavicle at 37-40 weeks of gestation. The fetal clavicle images were compared with adult male clavicle images. The texture features obtained from these images were used for analysis.

resultsNo difference was observed in bone formation and destruction markers between the two groups. However, the texture analysis of ultrasonographic images revealed similarities in the characteristics of fetal clavicles in pregnant women receiving vitamin D supplementation and those of adult male clavicles.

conclusionsVitamin D supplementation in pregnancy has significant positive effects on fetal bone maturation besides contributing to maternal bone health. Texture feature analyses using ultrasonographic images successfully demonstrated fetal bone maturation.

Indexed as

Bone DevelopmentClavicleFetal DevelopmentUltrasonography, PrenatalVitamin DAdultDietary SupplementsFemaleHumansMalePregnancyVitamin DFetal clavicleFetal clavicle ultrasonographyImage processingVitamin D

Identifiers

PMID39825247
PMCPMC11740525

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.