Evidence map›Paper›PMID 39825200›Full record

ArticleEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2025

Spontaneous otoacoustic emission as a novel method to screen pulsatile tinnitus caused by sigmoid sinus wall abnormalities: a prospective study.

Xu Liu, Yue-Lin Hsieh, Yunfeng Wang, Wuqing Wang

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Article in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Xu Liu *ENT Institute and Department of Otorhinolaryngology, Eye & ENT Hospital, Fudan University, Shanghai, 200031, China.ORCID http://orcid.org/0000-0001-5177-9948
Yue-Lin Hsieh *ENT Institute and Department of Otorhinolaryngology, Eye & ENT Hospital, Fudan University, Shanghai, 200031, China.ORCID http://orcid.org/0000-0002-1037-7659
Yunfeng WangENT Institute and Department of Otorhinolaryngology, Eye & ENT Hospital, Fudan University, Shanghai, 200031, China.ORCID http://orcid.org/0000-0001-7627-0929
Wuqing WangENT Institute and Department of Otorhinolaryngology, Eye & ENT Hospital, Fudan University, Shanghai, 200031, China. wwuqing@eent.shmu.edu.cn.ORCID http://orcid.org/0000-0002-7395-9525

Funding

Science and Technology Innovation Plan Of Shanghai Science and Technology Commission 22Y11902200
6 · The paper itself

Abstract

objectiveTo evaluate the diagnostic potential of spontaneous otoacoustic emissions (SOAE), distortion product otoacoustic emissions (DPOAE), and pure-tone audiometry (PTA) in patients with pulsatile tinnitus (PT) caused by sigmoid sinus wall anomalies (SSWA).

methodsThis study included 20 PT patients and 20 matched healthy controls. SOAE, DPOAE, and PTA were assessed before and after compression of the internal jugular vein. Statistical analysis included paired t-tests to compare differences in SOAE amplitude, DPOAE signal-to-noise ratios, and PTA thresholds, while independent t-tests assessed age differences, and one-way ANOVA evaluated mean PTA thresholds.

resultsSOAE amplitudes were significantly higher in ipsilesional ears compared to contralesional and control ears. DPOAE showed a significant difference in 0.5 kHz S/N-ratio between ipsilesional and contralesional ears. PTA revealed higher thresholds in ipsilesional ears at low frequencies, with differences decreasing after compression.

conclusionBesides radiological modalities, SOAE is a sensitive tool for diagnosing and assessing the severity of PT in patients with SSWA, with DPOAE and PTA providing supplementary information. These findings suggest a multimodal approach for the diagnosis of PT related to SSWA.

Indexed as

Cranial SinusesOtoacoustic Emissions, SpontaneousTinnitusAdultAgedAudiometry, Pure-ToneCase-Control StudiesFemaleHumansMaleMiddle AgedProspective StudiesYoung AdultExternal ear canal recordingHearingOtoacoustic emissionPulsatile tinnitusSigmoid sinus wall anomalies

Identifiers

PMID39825200

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.