Evidence map›Paper›PMID 39825008›Full record

ArticleAbdominal radiology (New York)2025

Preoperative prediction of tumor budding and lymphovascular invasion in colon cancer using dual-energy CT: a prospective study with internal model validation.

Chuanyang Shao, Changjiu He, Ping Zheng, Peng Zhou, Xiaoli Chen

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Article in Abdominal radiology (New York), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

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0cells of the map it votes in
3citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Chuanyang ShaoDepartment of Radiology, Radiation Oncology Key Laboratory of Sichuan Province, Sichuan Clinical Research Center for Cancer, Sichuan Cancer Hospital & Institute,. Sichuan Cancer Center, Affiliated Cancer Hospital of University of Electronic Science and Technology of China, 610000, Chengdu, China.
Changjiu HeDepartment of Radiology, Radiation Oncology Key Laboratory of Sichuan Province, Sichuan Clinical Research Center for Cancer, Sichuan Cancer Hospital & Institute,. Sichuan Cancer Center, Affiliated Cancer Hospital of University of Electronic Science and Technology of China, 610000, Chengdu, China.
Ping ZhengDepartment of Pathology, Sichuan Clinical Research Center for Cancer, Sichuan Cancer Hospital & Institute,. Sichuan Cancer Center, Affiliated Cancer Hospital of University of Electronic Science and Technology of China, 610000, Chengdu, China.
Peng ZhouDepartment of Radiology, Radiation Oncology Key Laboratory of Sichuan Province, Sichuan Clinical Research Center for Cancer, Sichuan Cancer Hospital & Institute,. Sichuan Cancer Center, Affiliated Cancer Hospital of University of Electronic Science and Technology of China, 610000, Chengdu, China.
Xiaoli ChenDepartment of Radiology, Radiation Oncology Key Laboratory of Sichuan Province, Sichuan Clinical Research Center for Cancer, Sichuan Cancer Hospital & Institute,. Sichuan Cancer Center, Affiliated Cancer Hospital of University of Electronic Science and Technology of China, 610000, Chengdu, China. 20shenbaise@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study evaluates the potential of dual-energy CT (DECT) for preoperative prediction of tumor budding (TB) and lymphovascular invasion (LVI) in colon cancer.

methodsThis prospective study enrolled 153 patients (mean age 61.33 years ± 0.88) with pathologically confirmed colon cancer. All participants underwent arterial and venous phase DECT scans within one week before surgery. Two radiologists independently analyzed the images, assessing tumor location, clinical N stage (cN stage), iodine concentration (IC), effective atomic number (Z-eff), and dual-energy index (DEI). The normalized iodine concentration (nIC) was obtained by comparing measured IC to the abdominal aortic IC. Logistic regression identified independent risk factors for high-grade TB and LVI positivity. The Akaike Information Criterion guided model selection, and the area under the curve (AUC) was calculated. Bootstrap validation with 1000 iterations was used for internal validation.

resultsTumor location and cN stage were identified as independent risk factors for high-grade TB, and nIC

conclusionDECT could consistently quantify colon cancer characteristics, and DECT-based models performed well in the preoperative prediction of TB and LVI.

Indexed as

Colonic NeoplasmsRadiography, Dual-Energy Scanned ProjectionTomography, X-Ray ComputedAgedContrast MediaFemaleHumansLymphatic MetastasisMaleMiddle AgedNeoplasm InvasivenessNeoplasm StagingPredictive Value of TestsPreoperative CareProspective StudiesContrast MediaColonic neoplasmsDual-energy computed tomographyIntestineLymphovascular invasionTumor budding

Identifiers

PMID39825008

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.