Evidence map›Paper›PMID 39824951›Full record

ArticleNPJ digital medicine2025

A scoping review of robustness concepts for machine learning in healthcare.

Alan Balendran, Céline Beji, Florie Bouvier, Ottavio Khalifa, Theodoros Evgeniou, Philippe Ravaud, Raphaël Porcher

Abstract read
In one paragraph

Article in NPJ digital medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Alan BalendranUniversité Paris Cité, Université Sorbonne Paris Nord, INSERM, INRAE, Centre for Research in Epidemiology and StatisticS (CRESS), Paris, France. alan.balendran@u-paris.fr.ORCID http://orcid.org/0000-0002-2779-458X
Céline BejiUniversité Paris Cité, Université Sorbonne Paris Nord, INSERM, INRAE, Centre for Research in Epidemiology and StatisticS (CRESS), Paris, France.
Florie BouvierUniversité Paris Cité, Université Sorbonne Paris Nord, INSERM, INRAE, Centre for Research in Epidemiology and StatisticS (CRESS), Paris, France.
Ottavio KhalifaUniversité Paris Cité, Université Sorbonne Paris Nord, INSERM, INRAE, Centre for Research in Epidemiology and StatisticS (CRESS), Paris, France.
Theodoros EvgeniouINSEAD Decision Sciences, Fontainebleau, France.ORCID http://orcid.org/0000-0001-9525-6110
Philippe RavaudUniversité Paris Cité, Université Sorbonne Paris Nord, INSERM, INRAE, Centre for Research in Epidemiology and StatisticS (CRESS), Paris, France.
Raphaël PorcherUniversité Paris Cité, Université Sorbonne Paris Nord, INSERM, INRAE, Centre for Research in Epidemiology and StatisticS (CRESS), Paris, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

While machine learning (ML)-based solutions-often referred to as artificial intelligence (AI) solutions-have demonstrated comparable or superior performance to human experts across various healthcare applications, their vulnerability to perturbations and stability to variations due to new environments-essentially, their robustness-remains ambiguous and often overlooked. In this review, we aimed to identify the types of robustness addressed in the literature for ML models in healthcare. A total of 274 eligible records were retrieved from PubMed, Web of Science, IEEE Xplore, and additional sources. Eight general concepts of robustness emerged. Furthermore, an analysis of those concepts across types of data and types of predictive models revealed that the concepts were differently addressed. Our findings offer valuable insights for stakeholders seeking to understand and navigate the robustness of machine learning models during their development, validation, and deployment in healthcare settings, where interpretation of robustness may vary.

Identifiers

PMID39824951
PMCPMC11742061

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.