Evidence map›Paper›PMID 39824924›Full record

ArticleScientific reports2025

In vitro antitumor effects of methanolic extracts of three Ganoderema mushrooms.

Elshahat A Toson, Amira A El-Fallal, Marwa A Oransa, Hoda M El-Gharabawy

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Elshahat A TosonChemistry Department, Faculty of Science, Damietta University, New Damietta, 34517, Egypt. eatoson@yahoo.com.
Amira A El-FallalBotany and Microbiology Department, Faculty of Science, Damietta University, New Damietta, 34517, Egypt.
Marwa A OransaBotany and Microbiology Department, Faculty of Science, Damietta University, New Damietta, 34517, Egypt.
Hoda M El-GharabawyBotany and Microbiology Department, Faculty of Science, Damietta University, New Damietta, 34517, Egypt. Hoda_mohamed@du.edu.eg.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ganoderma mushrooms have a variety of pharmacological activities and may have antitumor effects. Therefore, the antitumor activity of the methanolic fruiting body extracts of three Ganoderma spp. will be evaluated by estimating cell viability, cell cycle parameters and the mode of cellular death. In this regard, Sulfo-rhodamine B staining and flow cytometry were used. Hepatocellular carcinoma (HepG2) and breast ductal carcinoma (T-47D) cell lines were used as cancer models, while mouse normal liver (BNL) and oral epithelial cell (OEC) lines were used as respective controls. The results revealed that Ganoderma resinaceum extract decreased the viability of BNL at an IC

Indexed as

Antineoplastic AgentsGanodermaPlant ExtractsAgaricalesAnimalsApoptosisCell CycleCell Line, TumorCell ProliferationCell SurvivalFruiting Bodies, FungalHep G2 CellsHumansMethanolMiceAntineoplastic AgentsMethanolPlant ExtractsApoptosisBreast cancerCell line viabilityGanoderma spp.Liver cancerNecrosis

Identifiers

PMID39824924
PMCPMC11748650

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.